12,228 results found
    1. Cell Biology

    Single-cell analysis of skeletal muscle macrophages reveals age-associated functional subpopulations

    Linda K Krasniewski, Papiya Chakraborty ... Myriam Gorospe
    Single-cell analysis of skeletal mouse reveals highly diverse macrophage subgroups associated with diverse functions and age-related changes.
    1. Computational and Systems Biology

    Applying causal discovery to single-cell analyses using CausalCell

    Yujian Wen, Jielong Huang ... Hao Zhu
    Based on benchmarking various methods and analyzing multiple real scRNA-seq datasets, a computational platform/workflow and a set of tips for best practices are developed for analyzing causal interactions or relationships in single cells.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations

    Nir Drayman, Parthiv Patel ... Savaş Tay
    Single-cell analyses of cells infected by Herpes Simplex Virus 1 revealed extreme heterogeneity among infected cells, including the robust activation of developmental gene programs in highly infected cells.
    1. Computational and Systems Biology

    Multicellular factor analysis of single-cell data for a tissue-centric understanding of disease

    Ricardo Omar Ramirez Flores, Jan David Lanzer ... Julio Saez-Rodriguez
    A computational framework allows the unsupervised analysis of samples from single cell data across conditions, inference of multicellular programs associated with disease, and meta-analysis of independent patient cohorts.
    1. Microbiology and Infectious Disease

    Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state

    Miri Shnayder, Aharon Nachshon ... Michal Schwartz
    Single-cell and bulk expression analyses reveal that HCMV latent infection drives cells towards a weaker immune-responsive state, which is important for its expression and reactivation.
    1. Developmental Biology

    Single-cell profiling coupled with lineage analysis reveals vagal and sacral neural crest contributions to the developing enteric nervous system

    Jessica Jacobs-Li, Weiyi Tang ... Marianne E Bronner
    Single-cell transcriptome analysis of sacral compared with vagal neural crest-derived cells in the developing chick enteric nervous system reveals both similarities and differences between these two cell populations.
    1. Developmental Biology
    2. Genetics and Genomics

    Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris

    Brent A Wilkerson, Heather L Zebroski ... Olivia Bermingham-McDonogh
    The elucidation of the cellular composition of the crista and the genes expressed in each cell type is a critical step toward understanding inner ear development, function, and vestibulopathies.
    1. Immunology and Inflammation

    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator

    Takahisa Miyao, Maki Miyauchi ... Taishin Akiyama
    The combination of single-cell analysis and cell fate mapping studies evidenced the presence of AIRE-expressing transit-amplifying thymic epithelial cells, which differentiate into mature medullary thymic epithelial cells expressing tissue-specific antigens.
    1. Cancer Biology
    2. Computational and Systems Biology

    Mapping the single-cell landscape of acral melanoma and analysis of the molecular regulatory network of the tumor microenvironments

    Zan He, Zijuan Xin ... Hua Zhao
    A single-cell landscape of acral melanoma and the intermolecular regulatory relationships between microenvironments.
    1. Immunology and Inflammation

    Single-cell-level protein analysis revealing the roles of autoantigen-reactive B lymphocytes in autoimmune disease and the murine model

    Takemichi Fukasawa, Ayumi Yoshizaki ... Shinichi Sato
    Single-cell analysis revealed that autoantigen-reactive B cells changed the type of cytokines they produced from anti-inflammatory IL-10 and IL-35 to pro-inflammatory IL-6 and IL-23 as affinity to autoantigen increased.

Refine your results by:

Type
Research categories