Kai J Sandbrink, Pranav Mamidanna ... Alexander Mathis
To isolate and study proprioception, hierarchical deep neural networks paired with biomechanical models provide a normative approach to test the role of task effects on neural representations, such as the emergence of kinematic tuning and higher-level abstractions of actions.
The somatosensory cortex doesn't integrate mixed bilateral inputs, as partially uncrossing projections from the whiskers duplicates their representation by segregating lateralized inputs from each side of the head.
NMDAR receptors act in regulating axon guidance of somatosensory callosal projections in early postnatal life and the expression of EPHB2 receptors in target cells.
Kenneth Wengler, Andrew T Goldberg ... Guillermo Horga
fMRI evidence for distinct hierarchical alterations in intrinsic neural timescales for different positive symptoms of schizophrenia support hierarchical perceptual-inference models of psychosis and suggest local increases in excitation-inhibition ratio.
Naoki Yamawaki, Martinna G Raineri Tapies ... Gordon MG Shepherd
Cell-type-specific circuit analysis reveals a highly polysynaptic pattern of excitatory feedforward connections along the somatosensory-to-motor loop, from cuneate via VPL thalamus to S1 and M1 cortex and corticospinal neurons.
A combination of human imaging and brain stimulation techniques show that the somatosensory cortex is essential to prosocial decision making, by transforming observed pain in accurate perception of others' distress.