Cells control the spatial organization and signaling of TGFβ receptors at focal adhesions via a mechanically regulated mechanism to integrate biochemical and physical cues.

Two cooperative populations of yeast cells that cannot distinguish between cooperative partners and cheating intruders can still self-organize into clusters that exclude cheaters.

Transcriptome-scale RNA imaging and lifetime measurements reveal that the E. coli transcriptome is spatially organized and that this organization modulates the post-transcriptional fate of bacterial mRNAs.

A trait-based model of dryland vegetation uncovers the roles of spatial self-organization in maintaining biodiversity in a changing climate and offers novel ways of managing ecosystems at risk.

Single cell RNA–sequencing and neuroanatomical methods reveal unexpected molecular diversity and highly segregated spatial organization of neuronal cell types within the mouse ventral posterior hypothalamus, including the mammillary nuclei.

A computational framework allows the unsupervised analysis of samples from single cell data across conditions, inference of multicellular programs associated with disease, and meta-analysis of independent patient cohorts.

Genetic and biochemical analyses, coupled with fluorescence imaging, reveal that spatial compartmentalization of HMG-CoA Reductases at yeast ER-lysosome contacts modulates mevalonate pathway flux during glucose restriction, enabling metabolic adaptation.

Investigating microbial communities in a spatial environment in silico suggests that spatial structure promotes higher coexistence by allowing spatial self-organization, but can hinder coexistence by weakening interactions mediated through diffusible metabolites.

SCA-seq enables simultaneous detection of spatial interactions, chromatin accessibility, and CpG methylation at single-molecule resolution, advancing multi-omics studies of genome spatial organization.

The representation of the retina in early visual cortex shows that human brains have diverse functional organizations, raising questions about developmental mechanisms for visual map formation and how reliably these can be described by average templates.