648 results found
    1. Developmental Biology
    2. Genetics and Genomics

    Identification of CFAP52 as a novel diagnostic target of male infertility with defects of sperm head-tail connection and flagella development

    Hui-Juan Jin, Tiechao Ruan ... Su-Ren Chen
    CFAP52 is a candidate for genetic diagnosing male infertility with defects of sperm head-tail connection and flagella development.
    1. Ecology

    Adaptive thermal plasticity enhances sperm and egg performance in a model insect

    Ramakrishnan Vasudeva, Andreas Sutter ... Matthew JG Gage
    Sperm and egg development are temperature sensitive, enabling males and females to significantly improve their reproductive success by matching gamete function to varying thermal environments for fertilisation and offspring development.
    1. Chromosomes and Gene Expression

    An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning

    Ingrid Ehrmann, James H Crichton ... David J Elliott
    Cell division by meiosis during sperm production depends on expression of an RNA-binding protein that prevents abnormal RNA-processing pathways.
    1. Cell Biology
    2. Genetics and Genomics

    A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

    Maulik R Patel, Ganesh K Miriyala ... Harmit S Malik
    A 'male-harming' mtDNA mutation has been identified in Drosophila and impairs male fertility without impairing other male or female functions.
    1. Developmental Biology

    Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

    Wipawee Winuthayanon, Miranda L Bernhardt ... Carmen J Williams
    Cyclic estrogen signaling in oviduct epithelial cells suppresses oviduct luminal protease activity to allow survival and development of preimplantation embryos
    1. Genetics and Genomics

    Genetically engineered insects with sex-selection and genetic incompatibility enable population suppression

    Ambuj Upadhyay, Nathan R Feltman ... Michael Smanski
    Two distinct genetic biocontrol methods work synergistically to yield a novel approach in the fight against pest organisms.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells

    Kei Fukuda, Yoshinori Makino ... Yoichi Shinkai
    Bioinformatics analyses reveal that the Krüppel-associated box domain zinc finger proteins are associated with DNA methylation of retroelements in human primordial germ cells which highlight potential molecular mechanisms for the regulation of retroelements in human male germ cells.
    1. Cell Biology
    2. Genetics and Genomics

    An actin-related protein that is most highly expressed in Drosophila testes is critical for embryonic development

    Courtney M Schroeder, Sarah A Tomlin ... Harmit S Malik
    Non-canonical ‘testis-specific’ actin-related protein (Arp), Arp53D, is critical for early embryonic development in Drosophila, revealing important roles for lineage-specific, divergent, testis-expressed non-canonical Arps outside the male germline in animals.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Genome-wide detection of imprinted differentially methylated regions using nanopore sequencing

    Vahid Akbari, Jean-Michel Garant ... Steven JM Jones
    A genome-wide map of human allele-specific methylation using long-read sequencing detects novel imprinted DNA methylation events and reveals large blocks of subtle parent-of-origin bias in DNA methylation with mutual exclusive allelic H3K36me3 and H3K27me3 histone modifications.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Wolbachia action in the sperm produces developmentally deferred chromosome segregation defects during the Drosophila mid-blastula transition

    Brandt Warecki, Simon William Abraham Titen ... William Sullivan
    Differentiation of mitotic errors occurring during late embryonic development from the well-characterized first division defects provides new insight into the mechanisms of Wolbachia-induced cytoplasmic incompatibility.

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