1,492 results found
    1. Neuroscience

    All-trans retinoic acid induces synaptic plasticity in human cortical neurons

    Maximilian Lenz, Pia Kruse ... Andreas Vlachos
    The vitamin A derivative, all-trans retinoic acid, induces protein-synthesis-dependent synaptic plasticity in the human brain.
    1. Neuroscience

    The decoy SNARE Tomosyn sets tonic versus phasic release properties and is required for homeostatic synaptic plasticity

    Chad W Sauvola, Yulia Akbergenova ... J Troy Littleton
    Loss of the decoy SNARE Tomosyn enhances synaptic vesicle docking and neurotransmitter release and regulates release and plasticity differences between tonic and phasic motoneurons in Drosophila.
    1. Neuroscience

    Bidirectional synaptic plasticity rapidly modifies hippocampal representations

    Aaron D Milstein, Yiding Li ... Sandro Romani
    Dendritic calcium spikes translocate hippocampal place fields by inducing a non-Hebbian form of bidirectional synaptic plasticity that operates over a seconds-long timescale called behavioral timescale synaptic plasticity.
    1. Neuroscience

    Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

    Il Hwan Kim, Hong Wang ... Ryohei Yasuda
    Conditional knockout of the small GTPase Cdc42 in excitatory neurons of the mouse forebrain leads to impaired long-term synaptic plasticity and impaired retrieval of remote memory.
    1. Neuroscience

    Cell-specific synaptic plasticity induced by network oscillations

    Shota Zarnadze, Peter Bäuerle ... Tengis Gloveli
    Recordings of cellular and network activities of the mouse brain provide insights into how gamma rhythms contribute to memory formation.
    1. Neuroscience

    Energy efficient synaptic plasticity

    Ho Ling Li, Mark CW van Rossum
    The metabolic efficiency of learning in networks is improved by using forms of synaptic plasticity with different levels of persistence.
    1. Computational and Systems Biology
    2. Neuroscience

    Optimal plasticity for memory maintenance during ongoing synaptic change

    Dhruva V Raman, Timothy O'Leary
    Simple mathematical reasoning shows that the large amount of synaptic turnover seen in many parts of the brain is in fact optimal for memory retention.
    1. Computational and Systems Biology
    2. Neuroscience

    Evolving interpretable plasticity for spiking networks

    Jakob Jordan, Maximilian Schmidt ... Mihai A Petrovici
    Artificial evolution discovers biophysically plausible plasticity rules for spiking networks that perform competitively with and even outperform labor-intensive human-designed models in various learning scenarios, while providing new views on experimental data.
    1. Cell Biology
    2. Neuroscience

    AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity

    Josien Levenga, Helen Wong ... Charles A Hoeffer
    Three distinct AKT isoforms are found in the brain and show dissimilar patterns of expression, differential roles in the expression of synaptic plasticity, and different roles in neuronal signaling.
    1. Neuroscience

    Synaptic plasticity through activation of GluA3-containing AMPA-receptors

    Maria C Renner, Eva HH Albers ... Helmut W Kessels
    A novel form of hippocampal synaptic plasticity is expressed by a change in channel function of GluA3-containing AMPA-receptors.

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