Loading and linear translocation of condensin dosage compensation along the X-chromosomes create the loop-anchored topologically associating domains detected by Hi-C.

The iRhom2 protein, a catalytically inactive relative of rhomboid proteases, controls inflammation and growth factor signalling by acting as an essential multifunctional regulatory subunit of the cell surface shedding protease TACE (ADAM17).

Secretion of the inflammatory cytokine TNF requires a protein called iTAP/FrmD8, which controls the cell surface stability of the TNF shedding machinery, iRhom2 and TACE/ADAM17.

SARS-CoV-2 experienced ocrelizumab-treated MS patients benefit from SARS-CoV-2 mRNA vaccination by inducing broadprotective CD8+ T-cells, whereas methotrexate-treated RA patients induce delayed but strong antibody responses, which support vaccine strategies for these patient groups.

Deep immunophenotyping characterizes the genetic factors influencing immune functionality in patients with type 1 diabetes.

Transcranial alternating current stimulation modulates behavioral entrainment to sounds.

Non-invasive manipulation of endogenously coupled neural rhythms enhances human control of social-emotional actions.

Driving theta–gamma activity in the human cortex with non-invasive brain stimulation enhances motor skill acquisition in healthy adults, revealing a potential neuroplastic mechanism that might be harnessed for therapeutic intervention.

The molecular regulatory mechanisms that control the interaction between mesenchymal stem cells and transit amplifying cells to maintain tissue homeostasis.

Severing axons in C. elegans reveals a mechanism by which the axons sense acute damage and respond by sequential remodeling of their microtubule cytoskeleton.