The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.
Recurrent interactions in the optic tectum underlie activity-dependent changes in network state that account for variability in sensory encoding and behavior.
Andreas A Kardamakis, Juan Pérez-Fernández, Sten Grillner
Signals conveyed from two different senses from a given point in space converge onto the same neurons of the optic tectum that trigger the gaze-control-system, and at the same time inhibit other parts of the tectal motor map.
Han-Hsuan Liu, Daniel B McClatchy ... Hollis T Cline
A screen of visual-experience induced changes in newly-synthesized proteins in Xenopus optic tectum identifies unexpected candidate plasticity proteins.
Alison M Devault, Tatum D Mortimer ... Caitlin S Pepperell
Mineralized placental tissue from Late Byzantine Troy enables the detailed reconstruction of genomes of mixed bacterial species responsible for maternal sepsis in the ancient world.
Daniel L Felch, Arseny S Khakhalin, Carlos D Aizenman
During development, the Xenopus brain improves its ability to discern specific time intervals between sensory inputs of different modalities via the maturation of inhibitory circuits.
Dominique Förster, Thomas O Helmbrecht ... Herwig Baier
The retinotectal map in zebrafish exhibits location-specific, functional specializations to match prey object movement in the visual field during the hunting sequence.
Reward-related spatial information is preferentially represented in the lateral septum compared to the hippocampus and may be used downstream to direct the animal to rewarded locations.
Disrupting synapse formation between the retina and the brain in zebrafish larvae-by eliminating the molecular motor Kif5A-triggers a compensatory increase in the branching of retinal axons aimed at restoring synapse number.