702 results found
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish

    Shuguang Yu, Jie He
    The analysis of injury-reactivated tectal radial glia in zebrafish reveals a stochastic cell-cycle entry and cell-state-dependent regulation of the balance between neurogenesis and gliogenesis.
    1. Neuroscience

    Recurrent network interactions explain tectal response variability and experience-dependent behavior

    Asaph Zylbertal, Isaac H Bianco
    Recurrent interactions in the optic tectum underlie activity-dependent changes in network state that account for variability in sensory encoding and behavior.
    1. Neuroscience

    Spatiotemporal interplay between multisensory excitation and recruited inhibition in the lamprey optic tectum

    Andreas A Kardamakis, Juan Pérez-Fernández, Sten Grillner
    Signals conveyed from two different senses from a given point in space converge onto the same neurons of the optic tectum that trigger the gaze-control-system, and at the same time inhibit other parts of the tectal motor map.
    1. Neuroscience

    Role of the visual experience-dependent nascent proteome in neuronal plasticity

    Han-Hsuan Liu, Daniel B McClatchy ... Hollis T Cline
    A screen of visual-experience induced changes in newly-synthesized proteins in Xenopus optic tectum identifies unexpected candidate plasticity proteins.
    1. Neuroscience

    An NMDA receptor-dependent mechanism for subcellular segregation of sensory inputs in the tadpole optic tectum

    Ali S Hamodi, Zhenyu Liu, Kara G Pratt
    An activity-dependent mechanism sculpts subcellular segregation of sensory inputs.
    1. Microbiology and Infectious Disease

    A molecular portrait of maternal sepsis from Byzantine Troy

    Alison M Devault, Tatum D Mortimer ... Caitlin S Pepperell
    Mineralized placental tissue from Late Byzantine Troy enables the detailed reconstruction of genomes of mixed bacterial species responsible for maternal sepsis in the ancient world.
    1. Neuroscience

    Multisensory integration in the developing tectum is constrained by the balance of excitation and inhibition

    Daniel L Felch, Arseny S Khakhalin, Carlos D Aizenman
    During development, the Xenopus brain improves its ability to discern specific time intervals between sensory inputs of different modalities via the maturation of inhibitory circuits.
    1. Neuroscience

    Retinotectal circuitry of larval zebrafish is adapted to detection and pursuit of prey

    Dominique Förster, Thomas O Helmbrecht ... Herwig Baier
    The retinotectal map in zebrafish exhibits location-specific, functional specializations to match prey object movement in the visual field during the hunting sequence.
    1. Neuroscience

    Differences in reward biased spatial representations in the lateral septum and hippocampus

    Hannah S Wirtshafter, Matthew A Wilson
    Reward-related spatial information is preferentially represented in the lateral septum compared to the hippocampus and may be used downstream to direct the animal to rewarded locations.
    1. Neuroscience

    Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3

    Thomas O Auer, Tong Xiao ... Filippo Del Bene
    Disrupting synapse formation between the retina and the brain in zebrafish larvae-by eliminating the molecular motor Kif5A-triggers a compensatory increase in the branching of retinal axons aimed at restoring synapse number.

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