12,922 results found
    1. Cancer Biology
    2. Computational and Systems Biology

    Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records

    Jessica Xin Hjaltelin, Sif Ingibergsdóttir Novitski ... Søren Brunak
    A comprehensive comparison of the two types of pancreatic cancer symptom trajectories can in combination leverage a fuller potential of large health data and ultimately aid the detection of early risk factors for pancreatic cancer.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

    Isa Kristina Kirk, Christian Simon ... Søren Brunak
    Text mining of complete EHRs for 14,017 diabetes patients and subsequent clustering led to phenotypically deep clusters, showing distinct glycemic profiles, comorbidities, and SNP association patterns.
    1. Computational and Systems Biology

    Research: Bias in the reporting of sex and age in biomedical research on mouse models

    Oscar Flórez-Vargas, Andy Brass ... Goran Nenadic
    A text-mining study suggests that about half of the papers reporting the results of experiments on mice do not report the sex and age of the mice.
  1. Meta-Research: Investigating disagreement in the scientific literature

    Wout S Lamers, Kevin Boyack ... Dakota Murray
    An approach based on cue phrases can be used to identify instances of disagreement in scientific articles and compare the level of disagreement in various disciplines.
    1. Computational and Systems Biology

    Meta-Research: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines

    Zeljana Babic, Amanda Capes-Davis ... Anita E Bandrowski
    The use of Research Resource Identifiers (RRIDs) improves the proper use of cell lines in the biomedical literature.
    1. Physics of Living Systems
    2. Structural Biology and Molecular Biophysics

    Proofreading through spatial gradients

    Vahe Galstyan, Kabir Husain ... Rob Phillips
    Theoretical study shows how enzymes can achieve substrate proofreading by taking advantage of existing molecular gradients in the cell while not being endowed with structural features typically required for proofreading.
    1. Epidemiology and Global Health

    Reducing societal impacts of SARS-CoV-2 interventions through subnational implementation

    Mark M Dekker, Luc E Coffeng ... Sake J de Vlas
    An agent-based, population-scale, geographically explicit model, and integration of comprehensive data sources on demography, mobility, interactions and SARS-CoV-2 parameters, show that subnational implementations of intervention measures may provide better strategic choices for controlling future epidemics.
    1. Physics of Living Systems

    Physical observables to determine the nature of membrane-less cellular sub-compartments

    Mathias L Heltberg, Judith Miné-Hattab ... Thierry Mora
    Two competing descriptions of membrane-less sub-compartments, liquid droplets and polymer binding aggregates, can be cast into a common theoretical framework and tested through single-particle tracking experiments.
    1. Chromosomes and Gene Expression

    Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters

    Yi-Jun Sheu, Risa Karakida Kawaguchi ... Bruce Stillman
    The localization of Rad53 cell cycle checkpoint kinase to many gene promoters and the dynamic changes in response to replication stress suggests that the kinase may coordinate genome stability and gene expression.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Learning protein constitutive motifs from sequence data

    Jérôme Tubiana, Simona Cocco, Rémi Monasson
    A new machine-learning toolbox unveils coevolutionary protein motifs related to structure, function, and phylogeny from sequence information only.

Refine your results by:

Type
Research categories