1,925 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    Introgression shapes fruit color convergence in invasive Galápagos tomato

    Matthew JS Gibson, María de Lourdes Torres ... Leonie C Moyle
    A wild tomato species adopts local fruit color via introgression from an endemic relative, during its invasion onto the Galápagos Islands.
    1. Neuroscience

    Increased cortical plasticity leads to memory interference and enhanced hippocampal-cortical interactions

    Irene Navarro Lobato, Adrian Aleman-Zapata ... Lisa Genzel
    Increasing cortical plasticity leads to better one-trial memory but more interference effects on semantic-like memory.
    1. Plant Biology

    Tetraose steroidal glycoalkaloids from potato provide resistance against Alternaria solani and Colorado potato beetle

    Pieter J Wolters, Doret Wouters ... Vivianne GAA Vleeshouwers
    Chemical modifications of steroidal glycoalkaloids of potato can cause strong resistance against the necrotrophic early blight fungus as well as the Colorado potato beetle.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Pan-genome analysis identifies intersecting roles for Pseudomonas specialized metabolites in potato pathogen inhibition

    Alba Pacheco-Moreno, Francesca L Stefanato ... Andrew W Truman
    Genomics and genetics were used to identify specialized metabolites employed by Pseudomonas bacteria to suppress the growth of potato pathogens, which revealed a key role for cyclic lipopeptides.
    1. Stem Cells and Regenerative Medicine

    Generation of functional hepatocytes by forward programming with nuclear receptors

    Rute A Tomaz, Ekaterini D Zacharis ... Ludovic Vallier
    Forward programming of human pluripotent stem cells with a combination of four transcription factors allows the production of functional hepatocytes.
    1. Genetics and Genomics

    The rise and fall of the Phytophthora infestans lineage that triggered the Irish potato famine

    Kentaro Yoshida, Verena J Schuenemann ... Hernán A Burbano
    The strain of Phytophthora infestans that caused the Great Famine in the late 1840s was caused by a single genotype that is distinct from, but closely related to, the most prevalent modern genotype.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor

    Yasin F Dagdas, Khaoula Belhaj ... Tolga O Bozkurt
    A plant pathogen effector evolved a short linear motif to subvert autophagic defenses by antagonising a host cargo receptor.
    1. Neuroscience

    Long-term consequences of the absence of leptin signaling in early life

    Angela M Ramos-Lobo, Pryscila DS Teixeira ... Jose Donato Jr
    A mouse model that grew without functional leptin receptors until adulthood reveals that early defects in leptin signaling lead to permanent metabolic and developmental problems.
    1. Developmental Biology

    Hypertrophic chondrocytes serve as a reservoir for marrow-associated skeletal stem and progenitor cells, osteoblasts, and adipocytes during skeletal development

    Jason T Long, Abigail Leinroth ... Matthew J Hilton
    Hypertrophic chondrocytes of the growth plate undergo a process of dedifferentiation to generate marrow associated skeletal stem and progenitor cells (SSPCs), which ultimately re-differentiate into cells of the osteoblast or adipocyte lineages during skeletal development.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growth

    Francesca G Tomasi, Satoshi Kimura ... Matthew K Waldor
    Surveying Mycobacterium tuberculosis tRNA modification leads to identification of a modification promoting Mtb pathogenesis.

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