601 results found
    1. Neuroscience

    Emergence of transformation-tolerant representations of visual objects in rat lateral extrastriate cortex

    Sina Tafazoli, Houman Safaai ... Davide Zoccolan
    Neuronal recordings from rat visual cortex reveal an object-processing pathway, along which neuronal representations become increasingly capable of supporting recognition of visual objects in spite of variation in their appearance.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The glyoxylate shunt is essential for desiccation tolerance in C. elegans and budding yeast

    Cihan Erkut, Vamshidhar R Gade ... Teymuras V Kurzchalia
    Roundworms and yeast can survive extreme desiccation only by switching their metabolism into a gluconeogenic mode and producing very high amounts of trehalose via the glyoxylate shunt.
    1. Neuroscience

    Functional links between sensory representations, choice activity, and sensorimotor associations in parietal cortex

    Ting-Yu Chang, Raymond Doudlah ... Ari Rosenberg
    The fidelity of 3D visual object representations, choice-related activity, and experience-dependent sensorimotor associations are functionally linked in the caudal intraparietal area.
    1. Computational and Systems Biology
    2. Neuroscience

    Parallel processing, hierarchical transformations, and sensorimotor associations along the ‘where’ pathway

    Raymond Doudlah, Ting-Yu Chang ... Ari Rosenberg
    Hierarchical transformations of visual representations, saccade-related activity, and sensorimotor associations occur in parallel at the juncture of visual and parietal cortex.
    1. Plant Biology

    The Natural History of Model Organisms: The biology of C. richardii as a tool to understand plant evolution

    Sylvia P Kinosian, Paul G Wolf
    The natural history of the model fern Ceratopteris richardii provides opportunities for unique studies and makes it an important system to include in comparative work.
    1. Evolutionary Biology
    2. Neuroscience

    A small, computationally flexible network produces the phenotypic diversity of song recognition in crickets

    Jan Clemens, Stefan Schöneich ... Berthold Hedwig
    A computational model of the neuronal network that recognizes mating signals reveals network properties that support and constrain behavioral diversity in a species group.
    1. Ecology

    Genetic transformation of the dinoflagellate chloroplast

    Isabel C Nimmo, Adrian C Barbrook ... Christopher J Howe
    Successful stable transformation of the dinoflagellate chloroplast genome.
    1. Computational and Systems Biology

    Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting

    David Mavor, Kyle Barlow ... James S Fraser
    Chemical perturbation-dependent deep mutational scanning data collected by a lab-based interdisciplinary graduate class resolves a paradox between the high evolution conservation and the high mutational tolerance of the protein ubiquitin.
    1. Cancer Biology

    STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells

    Jong Wook Kim, Christian Berrios ... William C Hahn
    ST recruitment of STRIPAK facilitates PP2A-mediated dephosphorylation of MAP4K4 and induces cell transformation highlighting that STRIPAK complex plays a key role in defining PP2A specificity and activity.
    1. Cell Biology
    2. Cancer Biology

    A role for PVRL4-driven cell–cell interactions in tumorigenesis

    Natalya N Pavlova, Christian Pallasch ... Stephen J Elledge
    A protein called PVRL4 has a central role in a number of cancers that originate in epithelial tissue, and anti-PVRL4 antibodies could be used to treat some of these cancers.

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