316 results found
    1. Genetics and Genomics

    Non-allelic gene conversion enables rapid evolutionary change at multiple regulatory sites encoded by transposable elements

    Christopher E Ellison, Doris Bachtrog
    Fully functional regulatory elements can arise rapidly from transposable elements via a novel route where non-allelic gene conversion can act to speed up the evolutionary fine-tuning of regulatory elements.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Functional evaluation of transposable elements as enhancers in mouse embryonic and trophoblast stem cells

    Christopher D Todd, Özgen Deniz ... Miguel R Branco
    Genetic and epigenetic editing experiments establish causal links between transposon-derived enhancers and gene regulation in mouse embryonic and extraembryonic lineages.
    1. Genetics and Genomics

    Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution

    Yuh Chwen G Lee, Gary H Karpen
    The ability of transposable elements to epigenetically influence adjacent genes impacts genome evolution by driving substantial variation in transposon numbers between species.
    1. Evolutionary Biology

    Species-specific chromatin landscape determines how transposable elements shape genome evolution

    Yuheng Huang, Harsh Shukla, Yuh Chwen G Lee
    The ultimate driver for the substantial between-species difference in the success of transposable elements, the widely distributed genetic parasite, may lie in the overall chromatin environment.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The effect of hybridization on transposable element accumulation in an undomesticated fungal species

    Mathieu Hénault, Souhir Marsit ... Christian R Landry
    Transposable elements are not reactivated in natural hybrids of the yeast Saccharomyces paradoxus, but their accumulation is genotype-specific and is not predicted by the evolutionary divergence between a hybrid's parents.
    1. Evolutionary Biology

    Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs

    Michelle C Ward, Siming Zhao ... Yoav Gilad
    Human and chimpanzee-induced pluripotent stem cells show limited species-specificity in transposable element silencing.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Evolutionary dynamics of transposable elements in bdelloid rotifers

    Reuben W Nowell, Christopher G Wilson ... Timothy G Barraclough
    An investigation of transposable element evolution in a group of long-term asexual animals shows that many of the predicted effects of asexuality are not observed.
    1. Evolutionary Biology

    Asexual reproduction reduces transposable element load in experimental yeast populations

    Jens Bast, Kamil S Jaron ... Tanja Schwander
    Sexual reproduction is responsible for the evolutionary success of selfish transposable elements.
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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Population scale mapping of transposable element diversity reveals links to gene regulation and epigenomic variation

    Tim Stuart, Steven R Eichten ... Ryan Lister
    Fine mapping of transposable element presence/absence variation amongst 216 Arabidopsis strains uncovers widespread novel genetic diversity that underlies differences in transcription and DNA methylation patterns.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A population-level invasion by transposable elements triggers genome expansion in a fungal pathogen

    Ursula Oggenfuss, Thomas Badet ... Daniel Croll
    The activation of transposable elements and relaxed purifying selection underpin an incipient expansion of the genome in populations of a major wheat pathogen.

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