Laurent Jutras-Dubé, Ezzat El-Sherif, Paul François
Propagation, speed and shapes of genetic waves of expression during development can be modeled by a simple interplay between two transcriptional modules (dynamic/static), which explains robustness and precision of patterning.
An experimental and computational system has been developed to investigate how wavelike gene expression patterns are generated during embryonic development.
In transgenesis assays involving diploid model organisms, two clearly distinguishable transformation markers embedded in interweaved, but incompatible Lox site pairs allow the systematic creation of homozygous transgenic lines and minimize the number of wasted animals.
Maarten Hilbrant, Thorsten Horn ... Kristen A Panfilio
Late morphogenesis of the insect extraembryonic epithelia involves transient formation of a basal-basal bilayer to coordinate the functional contributions of two discrete tissues.
Erik Clark, Margherita Battistara, Matthew A Benton
A retracting gradient of the transcription factor Tailless spatiotemporally patterns the Drosophila tail region by modulating the intrinsic dynamics of a regulatory network involving the timer genes caudal, Dichaete, and odd-paired.