788 results found
    1. Neuroscience

    Sleep spindle maturity promotes slow oscillation-spindle coupling across child and adolescent development

    Ann-Kathrin Joechner, Michael A Hahn ... Markus Werkle-Bergner
    Across four samples of children, adolescents, and young adults, age-related higher similarity of dominant, development-specific fast sleep spindles and adult-like fast sleep spindles is uniquely related to stronger and more precise slow oscillation-sleep spindle coupling.
    1. Computational and Systems Biology

    Network design principle for robust oscillatory behaviors with respect to biological noise

    Lingxia Qiao, Zhi-Bo Zhang ... Lei Zhang
    Searching all two- and three-node gene regulatory network topologies identifies the repressilator with positive autoregulation as the motif capable of accurate oscillation and reveals the long period and high amplitude as two distinct mechanisms for buffering different noise.
    1. Neuroscience

    Vacillation, indecision and hesitation in moment-by-moment decoding of monkey motor cortex

    Matthew T Kaufman, Mark M Churchland ... Krishna V Shenoy
    Trial-by-trial analysis of neuronal activity in monkeys performing a decision-making task reveals the neural correlates of behaviours including wavering, hesitation and sudden changes of mind.
    1. Developmental Biology
    2. Neuroscience

    Slow oscillation-spindle coupling predicts enhanced memory formation from childhood to adolescence

    Michael A Hahn, Dominik Heib ... Randolph F Helfrich
    An individualized cross-frequency coupling approach identified slow oscillation-spindle coupling strength as a novel mechanism that mediates memory formation during cortical maturation.
    1. Neuroscience

    Network oscillation rules imposed by species-specific electrical coupling

    Stefanos Stagkourakis, Carolina Thörn Pérez ... Christian Broberger
    An unexpected species difference in electrical coupling of analogous neuroendocrine dopamine neurons in rats and mice reveals a role for gap junction connectivity as a band-pass filter for oscillation frequency in neural networks.
    1. Developmental Biology
    2. Neuroscience

    Slow oscillation–spindle coupling strength predicts real-life gross-motor learning in adolescents and adults

    Michael A Hahn, Kathrin Bothe ... Kerstin Hoedlmoser
    Individualized cross-frequency analyses reveal regionally specific slow oscillation–sleep spindle coupling precision as predictor for gross-motor learning dynamics.
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm, Florian Schmid ... Albrecht Stroh
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Neuroscience

    Impaired fast-spiking interneuron function in a genetic mouse model of depression

    Jonas-Frederic Sauer, Michael Strüber, Marlene Bartos
    Truncated Disrupted-in-schizophrenia 1 (Disc 1) ablates signaling of parvalbumin-expressing interneurons in the prefrontal cortex and underlies depression-related behaviour in mice.
    1. Neuroscience

    Prefrontal-amygdalar oscillations related to social behavior in mice

    Nahoko Kuga, Reimi Abe ... Takuya Sasaki
    The dorsal medial prefrontal cortex and basolateral amygdala exhibit social behavior-relevant neuronal oscillations, representing unified pathophysiological mechanisms underlying social behavioral deficits.
    1. Neuroscience

    Excitatory motor neurons are local oscillators for backward locomotion

    Shangbang Gao, Sihui Asuka Guan ... Mei Zhen
    Motor neurons are rhythm generators for backward locomotion.

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