An individual-based model estimates exogenous boosting of immunity following re-exposure to chickenpox is limited to 2 years after re-exposure, but an increase in herpes zoster incidence is still expected to occur following universal varicella vaccination.
Marcella M Cline, Barbara Juarez ... Larry S Zweifel
Genetic analysis of Ntn1 in adult mouse midbrain neurons reveals its function in maintaining excitatory synapses, loss of Ntn1 function in inhibitory neurons is significantly detrimental to mesolimbic system function.
ECM-Itgb1 signaling and cell-cell adhesion are pivotal and coordinate together to regulate pancreatic islet aggregation, architecture, and functional maturation during development.
Crystal Rock, Hector Zurita ... Alfonso junior Apicella
The discovery of somatostatin-positive inhibitory neurons projecting from mouse cortex to striatum shows that corticostriatal pathways are not exclusively excitatory.
José Lourenço, Maricelia Maia de Lima ... Mario Recker
An ento-epidemiological model reveals that what made the Zika virus a public health problem in Feira de Santana, Brazil, was a surprisingly high attack rate coupled with a low risk of Microcephaly per challenged pregnancy.
Brad K Hulse, Hannah Haberkern ... Vivek Jayaraman
An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.
Jeffrey R Adrion, Christopher B Cole ... Andrew D Kern
The stdpopsim library, a community-driven open source project, is presented which provides easy access to a standard catalog of published simulation models for population genetics aimed at field-wide standardization.
Biological wastewater treatment plants are critical reservoirs of antimicrobial resistance (AMR), allowing for early detection and monitoring of resistant pathogens, whilst serving as models for understanding the segregation of mobile genetic elements through AMR.
Electrophysiological recording and optogenetic manipulation approaches reveal that a multisensory bottom-up SC-LP-A1 pathway plays a role in contextual and cross-modality modulation of auditory cortical processing.
