3,851 results found
    1. Computational and Systems Biology
    2. Ecology

    Data-driven identification of potential Zika virus vectors

    Michelle V Evans, Tad A Dallas ... John M Drake
    Data-driven methods predict over 35 mosquitoes are potential vectors of Zika virus, suggesting a larger geographic area and a greater human population is at risk of infection.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    The contrasting phylodynamics of human influenza B viruses

    Dhanasekaran Vijaykrishna, Edward C Holmes ... Ian G Barr
    The analysis of the genomes of two lineages of influenza B virus (Victoria and Yamagata) reveal that their phylodynamics are fundamentally different, and are determined by a complex relationship between virus transmission, age of infection and receptor binding preference.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Principles of dengue virus evolvability derived from genotype-fitness maps in human and mosquito cells

    Patrick T Dolan, Shuhei Taguwa ... Judith Frydman
    Distinct selective landscapes in mosquito and human cells shape dengue virus genetic diversity and highlight mechanisms of host adaptation in arboviruses.
    1. Microbiology and Infectious Disease

    Unprecedented genomic diversity of RNA viruses in arthropods reveals the ancestry of negative-sense RNA viruses

    Ci-Xiu Li, Mang Shi ... Yong-Zhen Zhang
    Extensive genetic diversity and novel genome structures in RNA viruses from arthropods shed important new light on the ancestry and evolutionary history of major classes of vertebrate and plant viruses.
    1. Ecology
    2. Epidemiology and Global Health

    Predictors of human-infective RNA virus discovery in the United States, China, and Africa, an ecological study

    Feifei Zhang, Margo Chase-Topping ... Mark EJ Woolhouse
    In three different regions including the United States, China, and Africa, virus discoveries were strongly associated with GDP and land use, but were less likely to be associated with climate and biodiversity variables than at a global scale.
    1. Structural Biology and Molecular Biophysics

    The near-atomic cryoEM structure of a flexible filamentous plant virus shows homology of its coat protein with nucleoproteins of animal viruses

    Xabier Agirrezabala, Eduardo Méndez-López ... Mikel Valle
    The high-resolution structure of a filamentous flexible plant virus shows that there is structural homology between its coat protein and the nucleoproteins of an unrelated group of enveloped RNA animal viruses.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Parallel evolution between genomic segments of seasonal human influenza viruses reveals RNA-RNA relationships

    Jennifer E Jones, Valerie Le Sage ... Seema S Lakdawala
    Phylogenetic relationships between viral RNA segments are distinct between subtypes and lineages of seasonal human influenza A viruses and implicate RNA-RNA relationships as novel drivers of influenza virus evolution.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

    Alvin X Han, Zandra C Felix Garza ... Colin A Russell
    The longer duration of seasonal influenza virus infection in young children may provide opportunities for within-host evolution as a result of maintenance of genetic diversity through mutation-selection balance.
    1. Ecology
    2. Genetics and Genomics

    Viral dark matter and virus–host interactions resolved from publicly available microbial genomes

    Simon Roux, Steven J Hallam ... Matthew B Sullivan
    From public microbial genomes, VirSorter revealed 12,498 viral genome sequences that expand the map of the global virosphere and whose analyses improve understanding of viral taxonomy, evolution and virus-host interactions.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Discovery of several thousand highly diverse circular DNA viruses

    Michael J Tisza, Diana V Pastrana ... Christopher B Buck
    A bioinformatics pipeline has annotated over 2,500 complete genomes of circular DNA viruses belonging to dozens of established and emerging viral families.

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