33 results found
    1. Neuroscience

    Sex-specific processing of social cues in the medial amygdala

    Joseph F Bergan, Yoram Ben-Shaul, Catherine Dulac
    Male and female mice respond differently to the same pheromone signals, and the representation of these sensory stimuli by neurons in the medial amygdala correlates precisely with the differences in behavior.
    1. Developmental Biology
    2. Neuroscience

    Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2ε in vomeronasal sensory neurons

    Jennifer M Lin, Tyler A Mitchell ... Paolo Emanuele Forni
    In vivo genetic experiments show that aberrant expression of a transcription factor can compromise the functionality of neurons which is important to better understand the potential mechanisms underlying neuropathologies.
    1. Neuroscience

    Oxytocin signaling in the medial amygdala is required for sex discrimination of social cues

    Shenqin Yao, Joseph Bergan ... Catherine Dulac
    Oxytocin signaling plays a critical role in a molecularly defined neuronal population of the Medial Amygdala to modulate the behavioral and physiological responses of male mice to females on a moment-to-moment basis.
    1. Developmental Biology
    2. Neuroscience

    Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish

    Ankur Saxena, Brian N Peng, Marianne E Bronner
    Sensory neurons in the olfactory system develop from two different regions of the ectoderm, the olfactory placode and the cranial neural crest, whereas sensory neurons within the eye and ear develop from just one region.
    1. Cell Biology
    2. Evolutionary Biology

    Lifespan extension in female mice by early, transient exposure to adult female olfactory cues

    Michael Garratt, Ilkim Erturk ... Richard A Miller
    Early-life exposure to conspecific urine and bedding extends the lifespan of female mice, indicating that social chemosensory cues can influence aging in a mammal.
    1. Developmental Biology
    2. Genetics and Genomics

    Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism

    Samuel Andrew Malone, Georgios E Papadakis ... Paolo Giacobini
    Mouse in vivo and in vitro analysis and human genetic screening highlight the role of anti-Müllerian hormone (AMH) signaling in GnRH neuronal development and function, and identify mutations in AMH and AMHR2 in CHH patients.
    1. Neuroscience

    The activity-dependent histone variant H2BE modulates the life span of olfactory neurons

    Stephen W Santoro, Catherine Dulac
    A genome-organizing protein that is present only in the olfactory system of mice has been found to orchestrate changes in the relative numbers of different odor-sensing neurons on the basis of how active these neurons are.
    1. Neuroscience

    Integrated action of pheromone signals in promoting courtship behavior in male mice

    Sachiko Haga-Yamanaka, Limei Ma ... C Ron Yu
    Identification of two classes of mouse vomeronasal receptors for female pheromone cues suggests distinct gating mechanisms in pheromone-triggered reproductive behaviors.
    1. Neuroscience

    Unexplained repeated pregnancy loss is associated with altered perceptual and brain responses to men’s body-odor

    Liron Rozenkrantz, Reut Weissgross ... Noam Sobel
    Women with unexplained miscarriages have an altered behavioral and brain response to men's body-odor, and this may reflect a factor in their condition.
    1. Neuroscience

    Acquisition of innate odor preference depends on spontaneous and experiential activities during critical period

    Qiang Qiu, Yunming Wu ... C Ron Yu
    A delicate balance of neural activity is required during critical period in establishing innate odor preference.

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