273 results found
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Modularity and determinants of a (bi-)polarization control system from free-living and obligate intracellular bacteria

    Matthieu Bergé, Sébastien Campagne ... Patrick H Viollier
    Common ancestries, activities and structural determinants of a modular (bi-)polarization control system encoded in free-living and obligate intracellular α-proteobacteria, including the rickettsial pathogens, are described.
    1. Cell Biology

    Functional dichotomy and distinct nanoscale assemblies of a cell cycle-controlled bipolar zinc-finger regulator

    Johann Mignolet, Seamus Holden ... Patrick H Viollier
    Forward genetics and super-resolution microscopy identifies ZitP as a conserved multifunctional regulator that accumulates at both cell extremities in distinct macromolecular structures to perform different functions in the asymmetric model bacterium Caulobacter crescentus.
    1. Chromosomes and Gene Expression

    A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans

    Wei Jiang, Yuehua Wei ... Dengke K Ma
    A gene regulatory program regulating thermal stress response and organismic death.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans

    Amy L Roberts, Alessandro Morea ... Kerrin S Small
    Prospective, cross-sectional, and intra-twin study designs identify skewed X chromosome inactivation is associated with cardiovascular disease risk and future cancer diagnosis in the TwinsUK population cohort.
    1. Structural Biology and Molecular Biophysics

    A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins

    Danish Khan, Dongju Lee ... Vytas A Bankaitis
    A new class of fungal hemoproteins is described that emphasizes the versatility of the Sec14-fold for translating binding of chemically distinct ligands to control of diverse sets of cellular activities.
    1. Neuroscience

    Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice

    Panayiotis Tsokas, Changchi Hsieh ... Todd Charlton Sacktor
    The enzyme PKMzeta is crucial for the maintenance of long-term memories, but a closely related enzyme provides a back-up should PKMzeta fail, thus explaining the controversy over why deleting the gene for PKMzeta may not appear to impair memory.
    1. Neuroscience

    Dual-color optical activation and suppression of neurons with high temporal precision

    Noëmie Mermet-Joret, Andrea Moreno ... Sadegh Nabavi
    1. Cell Biology

    Pericentrin-mediated SAS-6 recruitment promotes centriole assembly

    Daisuke Ito, Sihem Zitouni ... Mónica Bettencourt-Dias
    Newly discovered interaction between fission yeast SPB and animal centriole components reveals that pericentrin not only functions as a microtubule-nucleator, but also promotes centriole assembly in animals.
    1. Neuroscience

    Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex

    Eric Kenji Lee, Hymavathy Balasubramanian ... Chandramouli Chandrasekaran
    WaveMAP is a novel approach that combines nonlinear dimensionality reduction with graph clustering on extracellular waveforms to reveal previously obscured cell type diversity in monkey cortex.
    1. Structural Biology and Molecular Biophysics

    Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitment

    James M Gibson, Heying Cui ... Chunyu Wang
    A cargo recognition α-helix was identified in Nup358, which is required for activation of a dynein-dependent transport pathway that is essential for brain development.

Refine your results by:

Type
Research categories