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    1. Neuroscience

    A contextual fear conditioning paradigm in head-fixed mice exploring virtual reality

    Seetha Krishnan, Can Dong ... Mark Sheffield
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Integration of sensory and fear memories in the rat medial temporal lobe: advancing research by Wong et al. (2019)

    Francesca S Wong, Alina B Thomas ... Nathan M Holmes
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

    Christopher Bell, Lukas Kilo ... Stefanie Ryglewski
    Mutually exclusive splicing of two exon pairs of the only Drosophila Cav2 homolog cacophony mediates functional diversity of Cav2 channels in Drosophila.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome

    Yan Zhao, Hanshuo Zhu ... Li Sun
    T3SS translocon induces NLRC4-mediated cell death via a conserved C-terminal region shared by many T3SS-positive bacterial pathogens.
    1. Microbiology and Infectious Disease

    Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody

    Manuela C Aguirre-Botero, Olga Pacios ... Rogerio Amino
    A late-neutralizing monoclonal antibody targeting the major surface antigen of plasmodial sporozoites impairs the fitness of intracellular parasites, offering mechanistic insights to guide the development of potent anti-malaria antibodies.
    1. Neuroscience

    Sleep need driven oscillation of glutamate synaptic phenotype

    Kaspar E Vogt, Ashwinikumar Kulkarni ... Robert W Greene
    Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of this LTP potential.
    1. Genetics and Genomics

    fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans

    Angela M Tuckowski, Safa Beydoun ... Scott F Leiser
    fmo-4 slows aging downstream of dietary restriction and mTOR and regulates calcium-mediated signaling in the hypodermis.
    1. Neuroscience

    Dual transcranial electromagnetic stimulation of the precuneus-hippocampus network boosts human long-term memory

    Ilaria Borghi, Lucia Mencarelli ... Giacomo Koch
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics

    Deficiency in DNAH12 causes male infertility by impairing DNAH1 and DNALI1 recruitment in humans and mice

    Menglei Yang, Hafiz Muhammad Jafar Hussain ... Baolu Shi
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    ElectroPhysiomeGAN: Generation of Biophysical Neuron Model Parameters from Recorded Electrophysiological Responses

    Jimin Kim, Minxian Peng ... Eli Shlizerman
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
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