Changes in the interactome of the Rel family of transcription factors control adaptation to the environmental stress of hyperosmolarity and determine cell fate.

An optogenetic approach has been developed to model Alzheimer's disease allowing light-induced Amyloid-β aggregation and tested in three model organisms, Drosophila, C. elegans and D. rerio.

Heterogeneous distances between vesicles and Ca²⁺-channels make synapses prone to short-term depression, however, Ca²⁺-dependent increases in the number of release-ready vesicles supports facilitation even with broadly distributed vesicle:Ca²⁺-channel distances.

Site-specific modification of NEMO facilitates RANKL signal specificity in myeloid progenitors and serves as a potential target to modulate inflammatory osteolysis through ISG15-dependent autophagy.

Electrophysiological recordings and a large-scale biophysical model show that a unique inhibitory neuron plays a central role in structuring olfactory codes in the insect brain.

A high-phytate-low Ca²⁺ diet causes crystal nephropathies, renal phosphate wasting, and bone disease in rats, whereas high Ca²⁺ intake ameliorates the detrimental effects of a high-phytate diet.

Rats are highly social animals that show complex social skills, which has not been acknowledged enough when controlling them in the wild and conducting research in the laboratory.

Enzymatic division of labor is identified as an enabling biochemical strategy for regulating a family of structurally diverse bioactive lipids.