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    1. Computational and Systems Biology
    2. Neuroscience

    Stable task information from an unstable neural population

    Michael E Rule et al.
    Analysis and modelling of sensorimotor neural activity shows how ongoing plasticity and appropriately tuned weights can cope with substantial ongoing changes in the neural code.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of protein kinase A

    Friederike Roger et al.
    The major cytosolic yeast peroxiredoxin Tsa1 controls aging and H2O2-resistance by inhibiting protein kinase A through a conserved cysteine in the catalytic subunit activation loop and not by scavenging H2O2.
    1. Computational and Systems Biology
    2. Neuroscience

    Dopamine role in learning and action inference

    Rafal Bogacz
    A mathematical model describes the function of dopaminergic neurons in both learning and action planning.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier

    Katina D Hulme et al.
    Hyperglycaemia increases influenza severity by damaging the pulmonary epithelial-endothelial barrier and increasing pulmonary oedema during Influenza A virus infection.
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    Innovation Leaders 2020: A summary

    We share some of the highlights, outcomes and learnings from our first open leadership and mentorship programme.
    1. Neuroscience

    Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability

    Yuliya Voskobiynyk et al.
    BIN1 forms a complex with Tau and voltage-gated calcium channels in neurons, and higher BIN1 levels promote neuronal activity, calcium influx, and bursting that is blocked by reducing Tau.
    1. Neuroscience

    Keratinocytes contribute to normal cold and heat sensation

    Katelyn E Sadler et al.