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    1. Ecology

    Genomic adaptations in information processing underpin trophic strategy in a whole-ecosystem nutrient enrichment experiment

    Jordan G Okie, Amisha T Poret-Peterson ... James J Elser
    Trait-based metagenomic analysis of an ecosystem fertilization experiment shows that genomic traits that affect the costs and rates of biochemical information-processing mediate community assembly.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Visualizing formation of the active site in the mitochondrial ribosome

    Viswanathan Chandrasekaran, Nirupa Desai ... V Ramakrishnan
    GTPBP7, NSUN4, and MTERF4 facilitate maturation of the peptidyl transferase center of the mitochondrial ribosome.
    1. Microbiology and Infectious Disease

    Bacterial DNA on the skin surface overrepresents the viable skin microbiome

    Ellen M Acosta, Katherine A Little ... Zemer Gitai
    The bacterial DNA on the surface of human and mouse skin is primarily from dead bacteria while viable skin microbiome bacteria mostly colonize subsurface skin structures like hair follicles.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Linking plasmid-based beta-lactamases to their bacterial hosts using single-cell fusion PCR

    Peter J Diebold, Felicia N New ... Ilana L Brito
    One-step Isolation and Lysis (OIL) PCR offers a robust, versatile, accessible, and high-throughput method for linking mobile DNA with bacterial hosts in natural microbial communities.
    1. Immunology and Inflammation

    Gut Helicobacter presentation by multiple dendritic cell subsets enables context-specific regulatory T cell generation

    Emilie V Russler-Germain, Jaeu Yi ... Chyi-Song Hsieh
    In vitro and in vivo studies show that multiple dendritic cell subsets are capable of presenting gut Helicobacter antigens to induce regulatory T cells.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium

    Jacob A Van Winkle, Stefan T Peterson ... Timothy J Nice
    The enteric bacterial microbiota stimulates a highly localized interferon-lambda signal within the intestinal epithelium that protects against murine rotavirus infection.
    1. Ecology
    2. Evolutionary Biology

    Interactions between strains govern the eco-evolutionary dynamics of microbial communities

    Akshit Goyal, Leonora S Bittleston ... Otto X Cordero
    Rapidly diversifying biotic interactions decouple the dynamics of nearly identical strains.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Major genetic discontinuity and novel toxigenic species in Clostridioides difficile taxonomy

    Daniel R Knight, Korakrit Imwattana ... Thomas V Riley
    The Clostridioides difficile taxonomy is characterised by major taxonomic incoherence and clear species boundaries.
    1. Ecology
    2. Microbiology and Infectious Disease

    Freshwater monitoring by nanopore sequencing

    Lara Urban, Andre Holzer ... Maximilian R Stammnitz
    From now on, nanopore metagenomics can be used to monitor aquatic environments with high spatiotemporal resolution, by use of a benchmarked, standardised and cost-effective workflow.
    1. Neuroscience

    Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

    Mar Gacias, Sevasti Gaspari ... Patrizia Casaccia
    Gut microbiota can influence mPFC transcriptional profiles and myelin content, overriding the impact of genetic background in the development of social avoidance behavior.