25 results found
    1. Evolutionary Biology
    2. Plant Biology

    Independent evolution of ancestral and novel defenses in a genus of toxic plants (Erysimum, Brassicaceae)

    Tobias Züst, Susan R Strickler ... Georg Jander
    A gain-of-function in a new chemical defense resulted in no trade-offs and and independent evolution between novel and ancestral defenses, suggesting low redundancy among different defensive chemicals.
    1. Microbiology and Infectious Disease

    Bacterial symbiont subpopulations have different roles in a deep-sea symbiosis

    Tjorven Hinzke, Manuel Kleiner ... Stephanie Markert
    Physiological differentiation during symbiosis leads to division of labor between smaller and larger cells in an uncultured bacterial tubeworm symbiont population and results in remarkable metabolic diversity and complexity.
    1. Plant Biology

    Adenylnucleotide-mediated binding of the PII-like protein SbtB contributes to controlling activity of the cyanobacterial bicarbonate transporter SbtA

    Britta Förster, Bratati Mukherjee ... G. Dean Price
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology

    A fat-2(wa17) suppressor screen in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency

    Delaney Kaper, Uroš Radović ... Marc Pilon
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Cell Biology
    2. Neuroscience

    The p38 MAP kinase pathway modulates the hypoxia response and glutamate receptor trafficking in aging neurons

    Eun Chan Park, Christopher Rongo
    The subcellular localization of the prolyl hydroxylase oxygen sensor in C. elegans neurons is regulated by p38 MAP kinase signaling.
    1. Cell Biology

    Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

    Ding Ding, Jie Zhang ... Le Kang
    The long-distance flight of locusts is greatly facilitated by a muscle-abundantly expressed Hif-1α splice variant, which remains active in normoxia and scavenges flight-induced reactive oxygen species by upregulating the expression of DJ-1 (PARK 7).
    1. Plant Biology

    Regulation of shoot meristem shape by photoperiodic signaling and phytohormones during floral induction of Arabidopsis

    Atsuko Kinoshita, Alice Vayssières ... George Coupland
    The shoot meristem becomes domed in shape during floral transition and this is controlled by flowering pathways and the phytohormone gibberellin causing increases in cell size and number.
    1. Genetics and Genomics

    IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming in a metabolic enzyme independent manner

    Mengjia Li, Hengchao Zhang ... Lixiang Chen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Cell Biology

    Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis

    Mark G Jones, Orestis G Andriotis ... Donna E Davies
    Nanoscale changes to individual collagen fibrils drive lung fibrosis.
    1. Chromosomes and Gene Expression

    Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases

    Ryan Janke, Anthony T Iavarone, Jasper Rine
    Mutations in budding yeast modeled after cancer-associated isocitrate dehydrogenase mutations lead to stabilization of heterochromatin and enhanced gene silencing through inhibition of specific histone demethylases by the oncometabolite D-2-hydroxyglutarate.

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