Browse the search results

Page 2 of 1,551
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition

    Maud Magdeleine, Romain Gautier ... Bruno Antonny
    The golgin GMAP-210 captures vesicles at the cis Golgi by merely recognizing the high curvature and lipid unsaturation level of transport vesicles.
    1. Structural Biology and Molecular Biophysics

    Discovery and characterization of Hv1-type proton channels in reef-building corals

    Gisela Rangel-Yescas, Cecilia Cervantes ... Leon D Islas
    Proton channels are present in reef-building corals and constitute important molecular players that should help understand calcification and the response of these organisms to ocean acidification.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Mechanism of chiral proofreading during translation of the genetic code

    Sadeem Ahmad, Satya Brata Routh ... Rajan Sankaranarayanan
    Structural biology has elucidated the mechanism of a configuration-specific enzyme that decouples D-amino acids from the translational machinery and, therefore, is involved in the enforcement of homochirality during protein synthesis.
    1. Cancer Biology

    Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology

    Timothy M Errington, Alexandria Denis ... Lisa Young
    A project to repeat experiments from high-impact papers in cancer biology did not complete all replications, with challenges ranging from mundane reasons to unexpected methodological issues.
    1. Microbiology and Infectious Disease

    Severe infections emerge from commensal bacteria by adaptive evolution

    Bernadette C Young, Chieh-Hsi Wu ... Daniel J Wilson
    Life-threatening S. aureus infections emerge from commensal nose bacteria in association with repeatable adaptive evolution.
    1. Epidemiology and Global Health

    Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

    Ellen A Kearney, Paul A Agius ... Freya JI Fowkes
    A systematic review with multilevel modelling quantified the positive association between human antibodies to Anopheles salivary proteins with Anopheles-human biting rate and epidemiological measures of malaria transmission, highlighting their potential as a tool to measure vector exposure and malaria transmission.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA

    David S Booth, Yifan Cheng, Alan D Frankel
    The nuclear export receptor Crm1 cooperatively binds its HIV Rev-RRE cargo as a dimer using a species-specific interface that supports viral replication by enhancing nuclear export of HIV RNA.
    1. Genetics and Genomics

    Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways

    Benoit Ballester, Alejandra Medina-Rivera ... Michael D Wilson
    Combinatorial transcription factor binding shared by multiple species enriches for essential biological pathways and coincides with disease-causing regulatory DNA mutations.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global divergence in critical income for adult and childhood survival: analyses of mortality using Michaelis–Menten

    Ryan J Hum, Prabhat Jha ... Yu-Ling Cheng
    A mathematical model based on enzyme kinetics shows how the relationships between life expectancy, survival rates for children and adults, and national income change over time.
    1. Neuroscience

    Functional dissociation of stimulus intensity encoding and predictive coding of pain in the insula

    Stephan Geuter, Sabrina Boll ... Christian Büchel
    Pain processing in certain brain regions implements predictive coding principles, offering a novel perspective on the neural basis of pain perception.