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    1. Genetics and Genomics
    2. Cancer Biology

    Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer

    Tackhoon Kim, Byung-Sun Park ... Timothy K Lu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Physics of Living Systems

    Single-molecule imaging reveals the role of membrane-binding motif and C-terminal domain of RNase E in its localization and diffusion in Escherichia coli

    Laura Troyer, Yu-Huan Wang ... Sangjin Kim
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Progesterone induces meiosis through two obligate co-receptors with PLA2 activity

    Nancy Nader, Lama Assaf ... Khaled Machaca
    Progesterone mediates nongenomic signaling in Xenopus oocyte meiosis by activating a PLA2 activity that requires two membrane receptors ABDH2 and mPRß.
    1. Neuroscience

    Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources

    Yating Liu, Guojing Tian ... Bin Qi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Chromosomes and Gene Expression

    Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response

    Jiayi Fan, Nalini Dhingra ... Xiaolan Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida

    Meina He, Yongxin Tao ... Wenli Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Multiplexed Assays of Human Disease-relevant Mutations Reveal UTR Dinucleotide Composition as a Major Determinant of RNA Stability

    Jia-Ying Su, Yun-Lin Wang ... Chien-Ling Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Identification of neurodevelopmental organization of the cell populations of juvenile Huntington’s disease using dorso-ventral HD organoids and HD mouse embryos

    Karolina Świtońska-Kurkowska, Jakub Kubiś ... Maciej Figiel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Microbiology and Infectious Disease

    DDX3 regulates the cap-independent translation of the Japanese encephalitis virus via its interactions with PABP1 and the untranslated regions of the viral genome

    Chenxi Li, Linjie Zhang ... Yanhua Li
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress

    Showkat Ahmad Dar, Sulochan Malla ... Manolis Maragkakis
    Cellular stress induces RNA decay that depends on stress granule assembly and is mediated by XRN1, independent of poly(A) tail and 5' cap removal.
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