Despite the virus' error prone polymerase, influenza virus antigenic evolution is rare, even in previously immune hosts, virus replication occurs before producing new antibodies.

Direct- and indirect pathway neurons of the posterior striatum display divergent in vivo and ex vivo plasticity after fear learning, and differentially modulate defensive behaviors displayed in the presence, and absence of threat-predicting sensory cues.

Isotope tracing, mathematical modeling, and single-cell ATP analysis reveal changes in blood cell metabolism under various conditions, showing stressed hematopoietic stem cells support hematopoiesis through glycolytic ATP production via PFKFB3.

Acute myeloid leukemia-specific predictive logic models reveal new therapeutic targets involved in cancer resistance mechanisms paving the way for personalized precision medicine.

Biologically plausible levels of myelin dystrophy induce substantial working memory impairment in a computational model of brain aging across two spatial and temporal scales.

ZAF (Zebrafish Automated Feeder) is the first fully automated, easy to build, and open source fish feeder designed for small and medium sized labs of which there are an estimated 3250 in 100 countries working with Zebrafish alone today.

By demonstrating song learning-related synaptic strengthening and pruning in the vocal control circuits of songbirds, and showing how such changes can reduce the sensitivity of the circuit to ‘noisy’ inputs, a simple neural circuit mechanism for regulating motor variability during motor skill learning is identified.

Botanists have long speculated about the adaptive value of visitor-triggered stamen movements, and here experiments that compare flowers with and without mobile stamens demonstrate large effects of stamen movements on pollen export, receipt, and nectar costs per pollen transport.

cyAbrB2, the global transcriptional factor conserved in cyanobacteria, is the nucleoid-associated protein, which is the first report in cyanobacteria.

Identifying and understanding that local anesthetic dyclonine targets TRPV3 channels will help to conceive therapeutic interventions.