149 results found
    1. Evolutionary Biology

    Not so local: the population genetics of convergent adaptation in maize and teosinte

    Silas Tittes, Anne Lorant ... Jeffrey Ross-Ibarra
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Screening the MMV Pathogen Box reveals the mitochondrial bc1-complex as a drug target in mature Toxoplasma gondii bradyzoites

    Deborah Maus, Elyzana Putrianti ... Martin Blume
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    RAS-p110a signalling in macrophages is required for effective inflammatory response and resolution of inflammation

    Alejandro Rosell, Agata A Krygowska ... Esther Castellano
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Microglia are Required for Developmental Specification of AgRP Innervation in the Hypothalamus of Offspring Exposed to Maternal High Fat Diet During Lactation

    Haley N Mendoza-Romero, Jessica E Biddinger ... Richard B Simerly
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cancer Biology

    Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing

    Einav Someach, Debdatta Halder ... Itay Tirosh
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    Novel risk loci for COVID-19 hospitalization among admixed American populations

    Silvia Diz-de Almeida, Raquel Cruz ... Ángel Carracedo
    Genetic association analyses in Latin American individuals revealed two additional loci associated with COVID-19 that were not previously found in other population groups.
    1. Cell Biology
    2. Immunology and Inflammation

    Arpin deficiency increases actomyosin contractility and vascular permeability

    Armando Montoya-Garcia, Idaira M Guerrero-Fonseca ... Michael Schnoor
    Arpin regulates actomyosin contractility and endothelial barrier integrity by controlling the activity of the kinases ROCK1 and ZIPK, but not Arp2/3.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody

    Joar Esteban Pinto Torres, Mathieu Claes ... Yann G.-J Sterckx
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Accelerated spike-triggered non-negative matrix factorization reveals coordinated ganglion cell subunit mosaics in the primate retina

    Sören J Zapp, Mohammad H Khani ... Tim Gollisch
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Elevated DNA Damage without signs of aging in the short-sleeping Mexican Cavefish

    Evan Lloyd, Fanning Xia ... Alex C Keene
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
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