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    1. Developmental Biology
    2. Evolutionary Biology

    Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes

    Hope M Healey, Hayden B Penn ... William A Cresko
    The production of a single-cell atlas for developing syngnathid fish permits study of their unique traits.
    1. Neuroscience

    An emerging view of neural geometry in motor cortex supports high-performance decoding

    Sean M Perkins, Elom A Amematsro ... Mark M Churchland
    Neural activity in motor cortex displays unexpected properties, making it possible to accurately decode behavior using a straightforward and interpretable approach.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Template switching during DNA replication is a prevalent source of adaptive gene amplification

    Julie N Chuong, Nadav Ben Nun ... David Gresham
    Template switching during DNA replication is a frequent source of adaptive gene amplification.
    1. Structural Biology and Molecular Biophysics

    Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments

    Jessica Flowers, Nathaniel Echols ... Stephanie A Wankowicz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    An image-computable model of speeded decision-making

    Paul I Jaffe, Gustavo X Santiago-Reyes ... Russell A Poldrack
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    The multifaceted role of the inferior colliculus in sensory prediction, reward processing, and decision-making

    Xinyu Du, Haoxuan Xu ... Xiongjie Yu
    The inferior colliculus integrates auditory and cognitive functions, playing critical roles in sensory prediction, reward processing, and decision-making beyond its traditional role as a sensory relay.
    1. Neuroscience

    Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI

    Joonas A Autio, Ikko Kimura ... Takuya Hayashi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience
    2. Physics of Living Systems

    A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

    Matthew Rozak, James Mester ... Bojana Stefanovic
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Risk factors affecting polygenic score performance across diverse cohorts

    Daniel Hui, Scott Dudek ... Marylyn D Ritchie
    Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.
    1. Neuroscience

    Auditory perception and neural representation of temporal fine structure are impaired by age but not by cochlear synaptopathy

    Friederike Steenken, Rainer Beutelmann ... Georg M Klump
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete