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    1. Genetics and Genomics

    A genome-wide association study implicates the olfactory system in Drosophila melanogaster diapause-associated lifespan extension and fecundity

    Sreesankar Easwaran, Denise J Montell
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Computational and Systems Biology
    2. Genetics and Genomics

    DGRPool, a web tool leveraging harmonized Drosophila Genetic Reference Panel phenotyping data for the study of complex traits

    Vincent Gardeux, Roel PJ Bevers ... Bart Deplancke
    The DGRPool web tool aggregates phenotyping data from the Drosophila Genetic Reference Panel, streamlining genetic association studies and offering new insights into genetic and phenotypic variation in complex traits.
    1. Biochemistry and Chemical Biology

    Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System

    Zeng-Hang Wang, Ying An ... Tao Dong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists

    Shristi Pawnikar, Brenda S Magenheimer ... Yinglong Miao
    Structural dynamic insights revealed the mechanisms of PC1 activation by stalk-derived peptide agonists which can form a foundation for development of PC1 as a therapeutic target for ADPKD treatment.
    1. Neuroscience

    AgRP1 modulates breeding season-dependent feeding behavior in female medaka

    Yurika Tagui, Shingo Takeda ... Chie Umatani
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Evolutionary Biology

    Pronounced expression of extracellular matrix proteoglycans regulated by Wnt pathway underlies the parallel evolution of lip hypertrophy in East African cichlids

    Nagatoshi Machii, Ryo Hatashima ... Masato Nikaido
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Massively Parallel Polyribosome Profiling Reveals Translation Defects of Human Disease-Relevant UTR Mutations

    Wei-Ping Li, Jia-Ying Su ... Chien-Ling Lin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    H2A.Z deposition at meiotic prophase I underlies homologous recombination and pachytene genome activation during male meiosis

    Shenfei Sun, Yamei Jiang ... Xinhua Lin
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Human receptive endometrial organoid for deciphering the implantation window

    Yu Zhang, Rusong Zhao ... Han Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

    José Antonio Valer, Alexandre Deber ... Francesc Ventura
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
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