Effect of CCL2 on HIV-1 replication is mediated by mobilization of ALIX from F-actin leading to enhanced virion release and improved fitness and this requires the Gag late motif, LYPX.
A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
Recent examples demonstrate that already the transcriptional activity at lncRNA genes does have an important function on gene regulation, while the produced non-coding RNA might be dispensable.
The concentration gradient of Bicoid protein positions gene expression domains along the anterior/posterior axis of the Drosophila embryo during the cleavage, pre-syncytial blastoderm stages.
Simultaneous measurements of neuronal activity and fMRI signals in the rat brain have shed new light on the origins of resting-state fMRI connectivity networks.
Differences in the response of cardiomyocytes to oxygen deprivation in humans and chimpanzees may explain why humans are more prone to certain heart diseases.