Histones bound to lipid droplets inside cells offer protection against bacteria in flies, and possibly mice, thus suggesting a possible new innate immunity pathway.
The transcription machinery used to regulate gene expression and self-renewal in human embryonic stem cells is different from that found in other cells.
A protein that can recognize regions of DNA with a high proportion of unmethylated CpG dinucleotides, and then recruit polycomb group proteins to these CpG islands, has been identified.
The ability of epithelial cells to distinguish between domains on opposing cell surfaces within a tissue, a property known as planar cell polarity, relies on proteins and protein complexes directing the traffic of signaling proteins to specific locations on the cell surface membrane.
Changing the order in which presynaptic and postsynaptic cells are repeatedly activated can change what a mammalian visual cortex neuron communicates to downstream neurons.
Neurons in the hippocampus modulate the rates at which they fire, and the locations in which they fire, so as to encode the information that is central to forming memories about personal experiences.
A transmembrane protein uses distinct mechanisms to regulate the movement of specific toll-like receptors-key immune system components involved in detecting pathogens-to their final locations inside cells.
