4,139 results found
    1. Ecology
    2. Evolutionary Biology

    Sexual dimorphism in trait variability and its eco-evolutionary and statistical implications

    Susanne RK Zajitschek et al.
    Sex differences in trait variability imply that both sexes should be included in biomedical trials, using sex-specific statistical power calculations.
    1. Developmental Biology
    2. Evolutionary Biology

    Secondary ossification center induces and protects growth plate structure

    Meng Xie et al.
    The principle underlying the appearance of the growth plate, an organ responsible for longitudinal growth, has implications for various cartilage pathologies including growth abnormalities in children, trauma and osteoarthritis.
    1. Developmental Biology
    2. Genetics and Genomics

    Smchd1 is a maternal effect gene required for genomic imprinting

    Iromi Wanigasuriya et al.
    Imprinted gene expression is set up during a critical window of early embryonic development, by the translation of parental imprints by oocyte-supplied Smchd1 into allele-specific gene silencing.
    1. Developmental Biology
    2. Genetics and Genomics

    Speciation and the developmental alarm clock

    Asher D Cutter, Joanna D Bundus
    Integrating speciation genetics with ontogeny can identify predictable rules in the molecular evolution of developmental pathways and in the accumulation of reproductive isolation as genomes diverge.
    1. Cell Biology

    A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1

    Natalia Felipe-Medina et al.
    Genetic and biochemical analysis reveal a variant in HSF2BP causing POI and C19ORF57/BRME1 as an interactor and stabilizer of HSF2BP by forming a complex with BRCA2, RAD51, RPA and PALB2.
    1. Neuroscience

    Integrative frontal-parietal dynamics supporting cognitive control

    Derek Evan Nee
    Analysis of human fMRI data reveal that intermediary areas within the fronto-parietal control network (FPCN) are critical for integrating control processing, cognitive ability, and amenability to neuromodulation.
    1. Evolutionary Biology

    New light shed on the early evolution of limb-bone growth plate and bone marrow

    Jordi Estefa et al.
    A three-dimensional investigation of extinct-tetrapod limbs shows that even though bone elongation and blood-cell production are intimately related to mammal long bones, these functions actually appeared successively in tetrapod evolution.
    1. Cell Biology

    Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface

    Abril Angélica Escamilla-Ayala et al.
    Super-resolution microscopy sets a new strategy to comprehend the membrane organization of γ-secretase at single complex resolution identifying nanodomain associations and its diffusion in situ in the living membrane.
    1. Neuroscience

    Dopamine neuron ensembles signal the content of sensory prediction errors

    Thomas A Stalnaker et al.
    Dopamine neurons function as an ensemble to signal a multidimensional feature prediction error.
    1. Neuroscience

    An afferent white matter pathway from the pulvinar to the amygdala facilitates fear recognition

    Jessica McFadyen et al.
    A subcortical white matter connection from the pulvinar to the amygdala predicts how well we recognise fearful faces and the strength of feed-forward neural connectivity.

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