Over 2.8 million tissue-specific gene regulatory sequences are predicted for 33 insect genomes, using a simple computational workflow with only the genome sequence and a basic gene annotation as input.
A new way to treat Zika virus infections could be achieved following the definition of an ion channel function for the M protein within virus particles.
An open-source tool for computational simulations of the human genome has been introduced, enabling the characterization of complex nuclear environments and the interpretation of experimental observations.
Brian G Vassallo, Noemie Scheidel ... Dennis H Kim
Distinct members of the Caenorhabditis elegans microbiota can have widely divergent effects on Orsay virus transmission, such that associated bacteria can effectively determine host susceptibility versus resistance to viral infection.
Molecular mechanism that Candidatus Liberibacter asiaticus improves the lipid metabolism and fecundity of Diaphorina citri through adipokinetic hormone and its receptor.
Nguyen Lam Vuong, Nguyen Than Ha Quyen ... Ronald Geskus
Higher plasma viremia levels in early dengue and a slower subsequent decline are associated with worse clinical outcomes and provide valuable outcome measures for future therapeutic intervention trials.
James W Truman, Lynn M Riddiford ... Michelle Herko
This sesquiterpene hormone likely acted as a morphogenesis-to-differentiation switch in archaic embryos before it evolved its postembryonic function as the status quo regulator of insect metamorphosis.