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    1. Ecology
    2. Microbiology and Infectious Disease

    Recurring patterns in bacterioplankton dynamics during coastal spring algae blooms

    Hanno Teeling et al.
    Dynamic successive blooms of clades of planktonic marine bacteria that can be observed during blooms of marine algae follow discernible patterns, part of which might be explained by substrate-induced forcing.
    1. Microbiology and Infectious Disease

    Quorum sensing control of Type VI secretion factors restricts the proliferation of quorum-sensing mutants

    Charlotte Majerczyk et al.
    Quorum-sensing control of Burkholderia thailandensis toxin and immunity pairs serves to police quorum-sensing mutants and may represent a general strategy whereby cooperators can police mutants.
    1. Evolutionary Biology

    The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts

    Patric M Vaelli et al.
    Skin-associated bacteria underlie the production of a potent defensive neurotoxin in newts, impacting host physiology, molecular evolution, and predator-prey interactions in a coevolutionary arms race.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog

    Oleg A Volkov et al.
    A catalytically dead paralog activates its cognate enzyme through an allosteric mechanism that combined structural and phylogenomic analysis indicates arose through acquisition of a dimerization domain, suggesting a general model for how complex allostery evolves.
    1. Microbiology and Infectious Disease

    Mechanistic Microbiome Studies: A Special Issue

    Edited by Wendy S Garrett et al.
    eLife is pleased to present a Special Issue to highlight recent advances in the mechanistic understanding of microbiome function.