DNA sequences from the Middle Pleistocene reveal that the extinct Eurasian straight-tusked elephants were closely related to today's African forest elephants (Loxodonta cyclotis) in Africa.

Elephants escaped enhanced cancer susceptibility by evolving more master tumor suppressor genes.

Duplication of tumor suppressor genes contributed to the evolution of large, long-lived elephants.

The evolutionary loss of the main enzyme required for ketone body biosynthesis suggests that alternative strategies to provide energy for large brains during fasting evolved repeatedly in mammals.

Sloths, armadillos, and anteaters evolved genetic and cellular traits that make them remarkably cancer resistant.

The new whale shark genome assembly represents the best gapless chondrichthyan genome assembly yet, and comparative genomic analyses provide insights into the evolution of vertebrate genome origins, immunity, and gigantism.