197 results found
    1. Structural Biology and Molecular Biophysics

    Enabling X-ray free electron laser crystallography for challenging biological systems from a limited number of crystals

    Monarin Uervirojnangkoorn et al.
    Post-refinement methods enable the use of X-ray free electron lasers for biological crystallography of systems in which sample quantity is a limitation.
    1. Neuroscience

    Freezing suppression by oxytocin in central amygdala allows alternate defensive behaviours and mother-pup interactions

    Elizabeth Rickenbacher et al.
    Oxytocin in the amygdala suppresses freezing of mothers when exposed to a threat in the presence of their offspring, allowing for pup protection and transmission of information about danger from mothers to pups.
    1. Medicine

    Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer

    Fernanda I Staquicini et al.
    A peptide motif targeting tumor-infiltrating macrophage in triple-negative breast cancer delays tumor growth and favors an antitumor immune response.
    1. Cell Biology
    2. Developmental Biology

    Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication

    Andrew Kodani et al.
    To control centriole duplication, centriolar satellite proteins assemble a microcephaly-associated protein complex at the centrosome and activate cyclin-dependent kinase 2.
    1. Epidemiology and Global Health

    A century of trends in adult human height

    NCD Risk Factor Collaboration (NCD-RisC)
    Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.
    1. Epidemiology and Global Health

    Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

    NCD Risk Factor Collaboration (NCD-RisC)
    Changes in the prevalence of underweight, total obesity, and severe obesity are largely driven by shifts in the distribution of body mass index.
  1. eLife Community Ambassadors: 243 volunteers join the programme in 2019

    Diverse researchers from across the world are joining forces to promote responsible behaviours in science.
    1. Developmental Biology
    2. Plant Biology

    A digital 3D reference atlas reveals cellular growth patterns shaping the Arabidopsis ovule

    Athul Vijayan et al.
    Deep imaging, machine-learning-based segmentation, and tissue annotation resulted in a developmental series of 3D digital ovules with cellular resolution allowing next-level analysis of the ontogenesis of this complex organ.
    1. Neuroscience

    Rapid computations of spectrotemporal prediction error support perception of degraded speech

    Ediz Sohoglu, Matthew H Davis
    Analysis of speech acoustics and human brain activity reveals the neural computations by which listeners combine speech input with prior expectations.
    1. Developmental Biology

    Antagonistic control of Caenorhabditis elegans germline stem cell proliferation and differentiation by PUF proteins FBF-1 and FBF-2

    Xiaobo Wang et al.
    Complementary effects of FBF-1 and FBF-2 on germline stem cell dynamics result from their distinct cooperation with mRNA deadenylase resulting in the opposite effects on the shared target mRNAs.

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