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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment

    Xinru Wang et al.
    A novel dynamic charge-charge interaction between B56 and a subset of PP2A-B56 substrates is essential for substrate specificity, dephosphorylation and, for KIF4A, binding condensin I.
    1. Biochemistry and Chemical Biology

    Control of the polyamine biosynthesis pathway by G2-quadruplexes

    Helen Louise Lightfoot et al.
    An ensemble of conserved G2-quadruplex structures in the untranslated regions of messenger RNAs from genes in the polyamine bioysynthesis pathway sense polyamine levels and regulate polyamine synthesis in cells.
    1. Developmental Biology
    2. Plant Biology

    Cross-species functional diversity within the PIN auxin efflux protein family

    Devin Lee O'Connor et al.
    Comparative genetics between distant plant species shows that for the PIN auxin transport proteins differential membrane and tissue-level accumulation, transport activity, and interaction result in different functional properties in the shoot post transcription.
    1. Developmental Biology
    2. Plant Biology

    Coordination of tissue cell polarity by auxin transport and signaling

    Carla Verna et al.
    GNOM controls both auxin transport and auxin signaling to coordinate tissue cell polarity during vein patterning in plants.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Transcriptome maps of general eukaryotic RNA degradation factors

    Salma Sohrabi-Jahromi et al.
    Mapping of 30 general RNA degradation factors onto the yeast transcriptome provides the global distribution of factors for RNA turnover and surveillance in a eukaryotic cell.
    1. Developmental Biology
    2. Plant Biology

    Quantitative analysis of auxin sensing in leaf primordia argues against proposed role in regulating leaf dorsoventrality

    Neha Bhatia et al.
    Top-bottom patterning of leaves is not specified by an asymmetry in the distribution of the plant hormone auxin, in contrast to a previous proposal.
    1. Developmental Biology
    2. Plant Biology

    Cell type boundaries organize plant development

    Monica Pia Caggiano et al.
    Leaf position, shape and orientation are pre-patterned by cell type boundaries in the shoot meristem.
    1. Cell Biology
    2. Developmental Biology

    Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy

    Naonobu Fujita et al.
    Analyses of a developmentally regulated Drosophila myofiber remodeling program provide insight into induced autophagy required for T-tubule membrane reorganization, and uncover a conserved Rab2 role in autophagosome-lysosome fusion.
    1. Cell Biology
    2. Plant Biology

    SnRK1-triggered switch of bZIP63 dimerization mediates the low-energy response in plants

    Andrea Mair et al.
    The transcription factor bZIP63 is a key regulator of the starvation response in the model plant Arabidopsis thaliana and is directly targeted by the kinase SnRK1.
    1. Developmental Biology
    2. Plant Biology

    Control of plant cell fate transitions by transcriptional and hormonal signals

    Christophe Gaillochet et al.
    HEC transcription factors control the timing of cell fate transitions in a dynamic stem cell system, allowing plants to adapt their developmental program to diverse environments.