485 results found
    1. Neuroscience

    Dismantling the Papez circuit for memory in rats

    Seralynne D Vann
    In contrast to current models, inputs from midbrain limbic structures, but not from the hippocampus, are necessary for mammillary body contributions to memory.
    1. Cell Biology
    2. Neuroscience

    Complete morphologies of basal forebrain cholinergic neurons in the mouse

    Hao Wu, John Williams, Jeremy Nathans
    The first complete 3D structures of mouse cholinergic neurons reveal the length and complexity of their axons, while calculations suggest that equivalent axons in the human brain are approximately than 100 meters long.
    1. Neuroscience

    Enhancement of fear memory by retrieval through reconsolidation

    Hotaka Fukushima, Yue Zhang ... Satoshi Kida
    Retrieval enhances fear memory through reconsolidation by activating calcineurin-induced protein degradation and CREB-mediated gene expression in amygdala, hippocampus, and mPFC.
    1. Neuroscience

    Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

    Il Hwan Kim, Hong Wang ... Ryohei Yasuda
    Conditional knockout of the small GTPase Cdc42 in excitatory neurons of the mouse forebrain leads to impaired long-term synaptic plasticity and impaired retrieval of remote memory.
    1. Neuroscience

    Human premotor areas parse sequences into their spatial and temporal features

    Katja Kornysheva, Jörn Diedrichsen
    Neuroimaging provides novel insights into how the motor system represents sequences of actions by automatically separating their spatial and temporal features for flexible skill production.
    1. Neuroscience

    Neural mechanisms of economic commitment in the human medial prefrontal cortex

    Konstantinos Tsetsos, Valentin Wyart ... Christopher Summerfield
    A striking dissociation exists in the medial prefrontal cortex, with different brain regions responding to value when commitments are deferred to the future and when prospects are judged to be undesirable.
    1. Neuroscience

    Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness

    Oluwaseun Akeju, Marco L Loggia ... Patrick L Purdon
    Patterns of communication between the thalamus and the cortex are correlated with anesthesia-induced loss of consciousness and recovery.
    1. Neuroscience

    Delay-dependent contributions of medial temporal lobe regions to episodic memory retrieval

    Maureen Ritchey, Maria E Montchal ... Charan Ranganath
    The anterior and posterior parts of the hippocampus have distinct roles in the retrieval of contextual information in memories of recent experiences.
    1. Neuroscience

    Ventromedial prefrontal cortex stimulation enhances memory and hippocampal neurogenesis in the middle-aged rats

    Albert Liu, Neeraj Jain ... Lee Wei Lim
    High-frequency stimulation of the ventromedial prefrontal cortex, which enhances memory and hippocampal neurogenesis, is a novel target for treatment of dementia-related diseases.
    1. Neuroscience

    Distinct effects of prefrontal and parietal cortex inactivations on an accumulation of evidence task in the rat

    Jeffrey C Erlich, Bingni W Brunton ... Carlos D Brody
    Quantitative modeling of inactivations shows the prefrontal cortex (but not parietal cortex) of the rat is obligatory for decisions guided by evidence accumulating longer than 240 ms.

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