Unbiased and automatic annotation using structured prediction framework with efficiently built data-driven atlases is more accurate than registration-based methods for cell identifications in dense images and enables fast whole-brain analysis.
Data-driven and effective connectivity analyses reveal patterns of functional specialization, common mechanisms, and brain-wide interaction profiles within the human inferior parietal lobes for multiple functional domains.
The ASAP initiative promotes open and collaborative practices, and works with other foundations and projects in an effort to understand the mechanisms responsible for the onset and progression of Parkinson's.
RNA binding protein FOX-1 functions as a dose-dependent X-signal element to communicate X-chromosome number and determine nematode sex by controlling alternative non-productive pre-mRNA splicing of the master sex-determination switch gene.
Spatially and temporally patterned activation of the small GTPase Rho1 indicates that ventral-specific factors contribute to cell- and tissue-level behaviors during ventral furrow formation, the first step in Drosophila gastrulation.