Proteomic profiling of extracellular vesicle proteins from patients with benign and malignant pancreatic diseases offers a valuable resource for identifying biomarkers for pancreatic cancer detection.

Differential colonization-extinction dynamics associated with species thermal preferences provide support for dispersal limitation and microclimate buffering as primary proxies by which habitat fragmentation mediates thermophilization in birds.

Unconventional secretion of a plasma membrane purine transporter via Golgi-bypass is established at an early ER-associated secretory compartment revealing that specific cargoes define alternative trafficking routes.

Single-cell RNA sequencing of biopsy samples from advanced-stage lung cancer reveals tumor and immune cell features associated with response to immune checkpoint therapy.

Antibody-mediated neutralisation of Gremlin-1 was ineffective in treating fibrosis in metabolic dysfunction-associated steatohepatitits, likely due to low hepatic expression in a subset of myofibroblasts and redundant Gremlin-1 signalling.

Salt stress triggers excessive hydrolysis of arginine-derived urea in Arabidopsis thaliana, raising cytoplasmic pH and inhibiting seed germination and seedling growth, providing new insights into the relationship between seed nitrogen mobilization and seed germination inhibition.