354 results found
    1. Neuroscience

    Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum

    Silas E Busch, Christian Hansel
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Disentangling acute motor deficits and adaptive responses evoked by the loss of cerebellar output

    Nirvik Sinha, Sharon Israely ... Yifat Prut
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Cortico-striatal action control inherent of opponent cognitive-motivational styles

    Cassandra Avila, Martin Sarter
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation

    Kelsey R Baron, Samantha Oviedo ... R Luke Wiseman
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques

    Nico A Flierman, Sue Ann Koay ... Chris I De Zeeuw
    Dentate nucleus neurons can dynamically modulate their activity during a visual attention task, comprising not only sensorimotor but also cognitive attentional components.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    p53 engagement is a hallmark of an unfolded protein response in the nucleus of mammalian cells

    Joseph H Park, Thomas J Wandless
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
    1. Cell Biology

    Pathogenic Huntingtin aggregates alter actin organization and cellular stiffness resulting in stalled clathrin-mediated endocytosis

    Surya Bansi Singh, Shatruhan Singh Rajput ... Deepa Subramanyam
    Neurodegeneration driven by pathogenic aggregating proteins reorganizes the actin cytoskeleton, causing cellular stiffening and abolishing force generation required for endocytic events.
    1. Neuroscience

    Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and a Community Resource

    Hugo Caffaratti, Ben Slater ... Christopher I Petkov
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics

    PDGFRα signaling regulates Srsf3 transcript binding to affect PI3K signaling and endosomal trafficking

    Thomas E Forman, Marcin P Sajek ... Katherine A Fantauzzo
    Upon PDGFRα signaling in mouse embryonic palatal mesenchyme cells, Srsf3 exhibits differential transcript binding, resulting in retention of the receptor in early endosomes and increased downstream PI3K-mediated Akt signaling.
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