240 results found
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Olivier Cochet-Escartin, Mete Demircigil ... Jean-Paul Rieu
    Cell assemblies can use environmental cues created by their own respiration, such as oxygen gradients, to collectively guide themselves to more favorable locations in a remarkably robust and long-lasting way.
    1. Immunology and Inflammation
    2. Neuroscience

    A microglia clonal inflammatory disorder in Alzheimer’s Disease

    Rocio Vicario, Stamatina Fragkogianni ... Frederic Geissmann
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Cancer Biology

    Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation

    Trang H Pham, Kanika Bajaj Pahuja ... Anwesha Dey
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Evolutionary Biology

    Evidence for deliberate burial of the dead by Homo naledi

    Lee R Berger, Tebogo Makhubela ... John Hawks
    Not revised
    Reviewed Preprint v1
    • Landmark
    • Inadequate
    1. Neuroscience

    Circuits for integrating learned and innate valences in the insect brain

    Claire Eschbach, Akira Fushiki ... Marta Zlatic
    Electron-microscopy reconstruction and experimental investigation in Drosophila reveal how adaptive action emerges from the multi-level interactions between the output of the olfactory memory center and the innate olfactory pathway.
    1. Genetics and Genomics
    2. Neuroscience

    The structure of behavioral variation within a genotype

    Zachary Werkhoven, Alyssa Bravin ... Benjamin L de Bivort
    Multidimensional analysis of data from high-throughput behavioral assays reveals many independent axes of behavioral variation among inbred animals reared in the same environment.
    1. Evolutionary Biology

    Burials and engravings in a small-brained hominin, Homo naledi, from the late Pleistocene: contexts and evolutionary implications

    Agustin Fuentes, Marc Kissel ... Lee R. Berger
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Evolutionary Biology

    241,000 to 335,000 Years Old Rock Engravings Made by Homo naledi in the Rising Star Cave system, South Africa

    Lee R. Berger, John Hawks ... Keneiloe Molopyane
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The neuronal calcium sensor NCS-1 regulates the phosphorylation state and activity of the Gα chaperone and GEF Ric-8A

    Daniel Muñoz-Reyes, Levi J McClelland ... Maria Jose Sanchez-Barrena
    Biochemical, biophysical, and structural approach to determine the molecular basis of the calcium-sensitive regulation of the Gα chaperone and guanine exchange factor Ric-8A by the neuronal calcium sensor NCS-1.

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