Lymphocytes and monocytes maintain their cell surface HLA-B via different mechanisms, which in turn differently influence cell-surface expression, half-life and peptide receptivity of HLA-B allotypes.
An innovative inter-subject stimulus-locked brain activation approach uncovers marked topological differences in a brain network of higher-order visual regions in individuals with a congenital impairment in face recognition compared with controls.
Spontaneous and evoked patterns of neural activity in the larval zebrafish tectum become less similar over development, in contrast with a previous hypothesis for the computational role of spontaneous activity.
A complementary relationship exists between the hemispheric lateralization of inhibitory control (typically right) and speech (typically left), as observed in typically and atypically lateralized left-handed individuals.
Cristina Gil Avila, Elisabeth S May ... Markus Ploner
Multiverse analysis of the aperiodic component of the electroencephalography (EEG) power spectrum yielded robust evidence against a relationship to chronic pain, guiding further research on EEG biomarkers of chronic pain.
Steven J Del Signore, Charlotte F Kelley ... Avital Adah Rodal
Autoinhibition allows synaptic endocytic actin regulators to pre-deploy to synaptic membranes at high concentrations and constrains actin assembly to productive events.
YQ Shirleen Soh, Louise H Moncla ... Jesse D Bloom
Complete mapping of human-adaptive mutations to the avian influenza PB2 protein shows how selection at key molecular interfaces combines with evolutionary accessibility to shape viral host adaptation.