2,693 results found
    1. Immunology and Inflammation

    Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity

    Brogan Yarzabek, Anita J Zaitouna ... Malini Raghavan
    Lymphocytes and monocytes maintain their cell surface HLA-B via different mechanisms, which in turn differently influence cell-surface expression, half-life and peptide receptivity of HLA-B allotypes.
    1. Neuroscience

    Altered topology of neural circuits in congenital prosopagnosia

    Gideon Rosenthal, Michal Tanzer ... Galia Avidan
    An innovative inter-subject stimulus-locked brain activation approach uncovers marked topological differences in a brain network of higher-order visual regions in individuals with a congenital impairment in face recognition compared with controls.
    1. Neuroscience

    Spontaneous and evoked activity patterns diverge over development

    Lilach Avitan, Zac Pujic ... Geoffrey J Goodhill
    Spontaneous and evoked patterns of neural activity in the larval zebrafish tectum become less similar over development, in contrast with a previous hypothesis for the computational role of spontaneous activity.
    1. Genetics and Genomics

    Spliceosome factors target timeless (tim) mRNA to control clock protein accumulation and circadian behavior in Drosophila

    Iryna Shakhmantsir, Soumyashant Nayak ... Amita Sehgal
    Alternative splicing provides a mechanism to maintain oscillations of the circadian clock.
    1. Neuroscience

    What happens to the inhibitory control functions of the right inferior frontal cortex when this area is dominant for language?

    Esteban Villar-Rodríguez, Cristina Cano-Melle ... César Avila
    A complementary relationship exists between the hemispheric lateralization of inhibitory control (typically right) and speech (typically left), as observed in typically and atypically lateralized left-handed individuals.
    1. Neuroscience

    Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG

    Cristina Gil Avila, Elisabeth S May ... Markus Ploner
    Multiverse analysis of the aperiodic component of the electroencephalography (EEG) power spectrum yielded robust evidence against a relationship to chronic pain, guiding further research on EEG biomarkers of chronic pain.
    1. Cell Biology
    2. Neuroscience

    An autoinhibitory clamp of actin assembly constrains and directs synaptic endocytosis

    Steven J Del Signore, Charlotte F Kelley ... Avital Adah Rodal
    Autoinhibition allows synaptic endocytic actin regulators to pre-deploy to synaptic membranes at high concentrations and constrains actin assembly to productive events.
    1. Neuroscience
    2. Genetics and Genomics

    Ecdysone acts through cortex glia to regulate sleep in Drosophila

    Yongjun Li, Paula Haynes ... Amita Sehgal
    Effects of ecdysone on sleep are mediated through lipid metabolism in cortex glia.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humans

    YQ Shirleen Soh, Louise H Moncla ... Jesse D Bloom
    Complete mapping of human-adaptive mutations to the avian influenza PB2 protein shows how selection at key molecular interfaces combines with evolutionary accessibility to shape viral host adaptation.
    1. Neuroscience

    Modulation of RNA processing genes during sleep-dependent memory

    Yongjun Li, Nitin S Chouhan ... Amita Sehgal
    RNA processing genes regulated during sleep-dependent memory may contribute to sleep and memory.

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