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    1. Cell Biology

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos

    Ryan M Finnerty, Daniel J Carulli ... Wipawee Winuthayanon
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology
    2. Medicine

    Procalcitonin for antimicrobial stewardship among cancer patients admitted with COVID-19

    Hiba Dagher, Anne-Marie Chaftari ... Issam Raad
    Procalcitonin could be useful in enhancing antimicrobial stewardship in cancer patients with COVID-19.
    1. Neuroscience

    Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment

    Qiu-Yan Xu, Yong-Jing Wang ... Tian-Ci Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cancer Biology
    2. Medicine

    A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation

    Jeffrey West, Fred Adler ... Alexander RA Anderson
    Open questions of cancer adaptive therapy are discussed through the lens of mathematical modeling, categorized into three sections, (1) integrating appropriate components into mathematical models, (2) dosing protocol design and validation, and (3) challenges and opportunities in clinical translation.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

    Joshua G Medina-Feliciano, Griselle Valentín-Tirado ... José E García-Arrarás
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration

    Hyunggu Hahn, Carole Daly ... Alex Rojas Bie Thomsen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Neuroscience

    The injured sciatic nerve atlas (iSNAT), insights into the cellular and molecular basis of neural tissue degeneration and regeneration

    Xiao-Feng Zhao, Lucas D Huffman ... Roman J Giger
    Single-cell analysis of injured mouse sciatic nerves reveals rapid reprogramming of macrophages toward a glycolytic, proinflammatory phenotype during the early repair process.
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Novel discoveries and enhanced genomic prediction from modelling genetic risk of cancer age-at-onset

    Ekaterina S. Maksimova, Sven E. Ojavee ... Matthew R. Robinson
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Deconstructing Complexity: A Computational Topology Approach to Trajectory Inference in the Human Thymus with tviblindi

    Jan Stuchly, David Novak ... Tomas Kalina
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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