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In the tumor microenvironment, only specific subsets of cytotoxic and immunosuppressive tumor-infiltrating lymphocytes are endowed with active translation.

B-cells generate inner actomyosin foci from lamellipodial actin networks to drive cell contraction on antigen-presenting surfaces, which causes signaling molecule disassociation from B-cell receptor clusters and signal attenuation.

A biochemical probe targeting Tregs shows the importance of Tregs for B cell homeostasis and peripheral B cell reduction is caused by an activated T-cell-dependent mechanism.

Transcriptional signature and cell morphology of the stroke-associated microglia are reprogrammed by distinct T cell subpopulations.

In years with colder ocean temperatures, fur seal pups receive more maternal care and have a better energy balance, clearing hookworm infection earlier, which increases their chances of survival.

The infection of T helper lymphocytes by SARS-CoV-2, mediated via the CD4 molecule, alters cellular function and enhances expression of the anti-inflammatory cytokine IL-10, potentially impairing immune response in individuals with COVID-19.

Quantitative protein and ribosome 'accounting' in T cells highlights a gap in our understanding of how activated T cells sufficiently replicate their proteome during rapid cell division driven by infection.

The common human HAQ,AQ alleles suppress STING1 gain-of-function mutation-induced chronic STING1 inflammation in mice.

Repeated interrogation of single germinal centers in vivo reveals a more fluid landscape than expected and unlocks new lines of investigation.

Genetic analyses reveal biological insight of a novel risk locus into systemic lupus erythematosus susceptibility.