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In cardiac ischemia/reperfusion injury, resident macrophages orchestrate the immune response and positively influence postinfarct remodeling, whereas recruited macrophages determine infarct size.

Isl2 orchestrates specific hindlimb motor pool arrangement, guaranteeing accurate motor control and sensorimotor circuit functionality.

LncRNA Neat1, with paraspeckle proteins, controls translational induction of (lymph)angiogenic and cardioprotective factors by the IRES-dependent mechanism in mouse cardiomyocytes submitted to hypoxia.

Asymmetrical expression dictates functional dominance of one STAT5 paralog at cellular and tissue levels despite redundancy at molecular and genomic levels.

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

The enteric bacterial microbiota stimulates a highly localized interferon-lambda signal within the intestinal epithelium that protects against murine rotavirus infection.

Forward genetic screening has provided insight into the molecular mechanisms and stress pathways that promote tumor cell recognition by natural killer cells.

ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, and its homolog ARID1B function to maintain chromatin accessibility and active histone modifications at enhancers.

A SWI/SNF-family chromatin remodeling subcomplex from yeast is identified (RSC1) that is specialized to slide nucleosomes residing on DNA sequences that confer partial nucleosome unwrapping, with assistance from accessory factors.