153 results found
    1. Cancer Biology

    Mice deficient of Myc super-enhancer region reveal differential control mechanism between normal and pathological growth

    Kashyap Dave et al.
    A tumor-specific regulatory region has been identified upstream of the Myc oncogene.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Hsp70-associated chaperones have a critical role in buffering protein production costs

    Zoltán Farkas et al.
    Protein biosynthesis and protein quality control jointly determine protein production costs.
    1. Chromosomes and Gene Expression

    MukB ATPases are regulated independently by the N- and C-terminal domains of MukF kleisin

    Katarzyna Zawadzka et al.
    In Escherichia coli structural maintenance of chromosomes (SMC) complex, MukBEF, a dimeric MukF kleisin binds and activates MukB SMC ATPases through two independent interfaces provided by distinct MukF N- and C-terminal domains.
    1. Neuroscience

    Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators

    Kristen M Smith-Edwards et al.
    Inflammatory pain, previously thought to result from increased activity in "pain" neurons, may in fact be due to wholesale changes in afferent output that includes increased and decreased activity that the brain interprets as pain.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Combinatorial bZIP dimers display complex DNA-binding specificity landscapes

    José A Rodríguez-Martínez et al.
    Cognate site identification uncovers the impact of combinatorial dimerization in specifying new DNA binding sites for human bZIP transcription factors and comprehensive specificity landscapes predict the impact of SNPs on bZIP binding at previously unannotated regulatory loci.
    1. Neuroscience

    Promoting subjective preferences in simple economic choices during nap

    Sizhi Ai et al.
    Neurocognitive processing during sleep selectively biases subjective preferences in simple economic choices when the sleeper is stimulated by covert, reward-associated cues.
    1. Cell Biology
    2. Computational and Systems Biology

    Remote control of microtubule plus-end dynamics and function from the minus-end

    Xiuzhen Chen et al.
    A mechanism for yeast centrosomes to differentiate the microtubule cytoskeleton.
    1. Computational and Systems Biology
    2. Neuroscience

    Dynamic range adaptation in primary motor cortical populations

    Robert G Rasmussen et al.
    Motor neurons adjust their sensitivity to direction of movement in a manner analogous to how neurons in the visual system adjust their sensitivity to light.
    1. Genetics and Genomics
    2. Neuroscience

    Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes

    Yehudit Hasin-Brumshtein et al.
    In depth characterization of gene expression in the mouse hypothalamus will facilitate understanding of the molecular pathways that affect metabolic traits and discovers new genes associated with these pathways.
    1. Neuroscience

    A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity

    Masahiro Yamashita et al.
    Human neuroimaging and machine learning reveals a generalizable relationship between brain connectivity and working memory ability across healthy populations and distinct psychiatric diagnoses.

Refine your results by:

Type
Research categories