4,133 results found
    1. Neuroscience

    Using an achiasmic human visual system to quantify the relationship between the fMRI BOLD signal and neural response

    Pinglei Bao et al.
    The lower-level retinotopic visual cortex of humans born without the optic chiasm comprises two independent neuronal populations and forms a versatile model for quantifying the relationship between the fMRI BOLD signal and neural response.
    1. Chromosomes and Gene Expression

    A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans

    Wei Jiang et al.
    A gene regulatory program regulating thermal stress response and organismic death.
    1. Stem Cells and Regenerative Medicine

    Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold

    Tomoya Hasegawa et al.
    The Interleukin 1 beta signaling and tissue inflammation act as a double-edged sword: they are required for regeneration, but when in excess, they impair tissue regeneration and induce apoptosis.
    1. Neuroscience

    What the success of brain imaging implies about the neural code

    Olivia Guest, Bradley C Love
    For brain imaging to be useful despite its limitations in measuring neural activity, the neural code must be smooth both in a traditional sense and functionally.
    1. Biochemistry and Chemical Biology

    AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis

    Sandra Galic et al.
    A single mutation in acetyl-CoA carboxylase blocking AMPK regulation inhibits food intake in mice in response to cold exposure or fasting causing them to lose weight.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Definition of two agonist types at the mammalian cold-activated channel TRPM8

    Annelies Janssens et al.
    Two natural cooling agents activate the cold-activated channel TRPM8 via two opposite mechanisms, evoking distinct electrical responses in cold-sensitive neurons.
    1. Neuroscience

    Amyotrophic Lateral Sclerosis: Marking the differences in motoneurons

    Simon A Sharples, Patrick J Whelan
    A subgroup of the neurons that control muscles becomes less excitable shortly before the symptoms of ALS develop.
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  1. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.

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