10 results found
    1. Neuroscience

    Urodynamics: How the brain controls urination

    Anna P Malykhina
    Coordination between the brainstem and the cortex helps to ensure that urination occurs at an appropriate time.
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    1. Neuroscience

    Brainstem network dynamics underlying the encoding of bladder information

    Anitha Manohar et al.
    Neural and network activity within a pontine-cortical micturition circuit are finely coordinated with urodynamics to assure appropriate voiding behaviors.
    1. Developmental Biology and Stem Cells
    2. Neuroscience

    Homeodomain protein Otp affects developmental neuropeptide switching in oxytocin neurons associated with a long-term effect on social behavior

    Einav Wircer et al.
    Experiments in zebrafish reveal a new role for a critical hypothalamic transcription factor, orthopedia, in controlling developmental neuropeptide balance in a discrete oxytocin-producing neuronal circuit whose disrupted development affects social behavior.
    1. Biophysics and Structural Biology
    2. Genes and Chromosomes

    RNA Polymerase II cluster dynamics predict mRNA output in living cells

    Won-Ki Cho et al.
    Quantitative super resolution imaging, in live mammalian cells, reveals a direct relationship between protein clustering dynamics and the number of mRNA transcribed at an endogenous gene locus.
    1. Neuroscience

    A dedicated visual pathway for prey detection in larval zebrafish

    Julia L Semmelhack et al.
    A subset of retinal ganglion cells respond specifically to small moving objects and project to a visual area that plays a key role in prey capture behavior.
    1. Cell Biology
    2. Genes and Chromosomes

    Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres

    Jan Wisniewski et al.
    Internally tagged, functional Cse4/CENP-A/CenH3 histone variant is exclusively centromeric and stable through the budding yeast cell cycle after replacement in S phase.
    1. Neuroscience

    Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion

    Timothy W Dunn et al.
    Whole-brain activity imaging in larval zebrafish reveals brain regions that influence patterns of spontaneous movement to increase local exploration efficiency.
    1. Cell Biology

    Homeostatic control of START through negative feedback between Cln3-Cdk1 and Rim15/Greatwall kinase in budding yeast

    Nicolas Talarek et al.
    Inhibition of phosphatases by kinases develops Whi5 phosphorylation and cell cycle function in low cyclin-dependent kinase activity.
    1. Neuroscience

    Peripheral optogenetic stimulation induces whisker movement and sensory perception in head-fixed mice

    Sunmee Park et al.
    Light can be used to trigger the contraction of facial muscles and movement of the whiskers in transgenic mice, aiding the study of active sensation.
    1. Biochemistry
    2. Immunology

    Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies

    Stephen R Daley et al.
    A single point mutation in a Ras activator leads to aberrant constitutive mTOR signaling in peripheral T cells that consequently accumulate as abnormal T helper cells and stimulate the production of autoantibodies by B cells.

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