628 results found
    1. Neuroscience

    Bayesian analysis of retinotopic maps

    Noah C Benson, Jonathan Winawer
    A novel Bayesian method of modeling retinotopic maps is more accurate than traditional voxel-wise methods and can be used to automatically derive high-quality maps.
    1. Computational and Systems Biology

    Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes

    Juliane Liepe et al.
    Experimental and computational analyses reveal how proteasomal hydrolysis is regulated and show that peptide transport is the rate-limiting step and the main differentiating factor between human standard- and immuno-proteasomes.
    1. Computational and Systems Biology

    Inferring joint sequence-structural determinants of protein functional specificity

    Andrew F Neuwald et al.
    A statistical approach for predicting non-active site residues responsible for allostery, cooperativity, or other subtle but functionally important interactions is described and applied to various protein families.
    1. Neuroscience

    Active sensing in the categorization of visual patterns

    Scott Cheng-Hsin Yang et al.
    Humans use a near-optimal eye movement strategy to efficiently extract information about high-level visual categories.
    1. Computational and Systems Biology

    Science Forum: Wikidata as a knowledge graph for the life sciences

    Andra Waagmeester et al.
    Wikidata is continuously-updated resource that could improve the efficiency and accuracy of research in many areas of the life and biomedical sciences.
    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
  1. Research: Publication bias and the canonization of false facts

    Silas Boye Nissen et al.
    Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.
  2. Meta-Research: The growth of acronyms in the scientific literature

    Adrian Barnett, Zoe Doubleday
    A study of 24 million articles has revealed that scientists have created more than 1 million acronyms since 1950, most of which have been used fewer than 10 times.
    1. Medicine

    Adverse Drug Reactions: The benefits of data mining

    Audrey Bone, Keith Houck
    Careful analysis of a database populated by physicians and patients sheds new light on the side effects of drugs.
    Insight
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  3. Cutting Edge: Science hackathons for developing interdisciplinary research and collaborations

    Derek Groen, Ben Calderhead
    Science hackathons can help academics, particularly those in the early stage of their careers, to build collaborations and write research proposals.

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