1,542 results found
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genetic factors of bilaterian evolution

    Peter Heger, Wen Zheng ... Thomas Wiehe
    Advanced orthology clustering of bilaterian and non-bilaterian sequences identifies 157 bilaterian-specific genes which are linked to key morphological features of this animal group.
    1. Evolutionary Biology
    2. Structural Biology and Molecular Biophysics

    Peripheral and central employment of acid-sensing ion channels during early bilaterian evolution

    Josep Martí-Solans, Aina Børve ... Timothy Lynagh
    Expression patterns and biophysical properties of acid-sensing ion channels in numerous bilaterian animals offer insight into the deployment of ion channels by the evolving nervous system in complex animals.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Insights into early animal evolution from the genome of the xenacoelomorph worm Xenoturbella bocki

    Philipp H Schiffer, Paschalis Natsidis ... Maximilian J Telford
    A genome analysis of Xenoturbella bocki provides insights into the biology of this enigmatic marine worm and enhances our understanding of early bilaterian evolution.
    1. Neuroscience

    Generative network modeling reveals quantitative definitions of bilateral symmetry exhibited by a whole insect brain connectome

    Benjamin D Pedigo, Mike Powell ... Joshua T Vogelstein
    Novel statistical tests to compare networks enable the evaluation of mathematical definitions of left/right symmetry in a larval Drosophila brain connectome.
    1. Neuroscience

    The impact of bilateral ongoing activity on evoked responses in mouse cortex

    Daisuke Shimaoka, Nicholas A Steinmetz ... Matteo Carandini
    Spontaneous bilateral fluctuations add with evoked cortical activity and explain much of the variability in sensory responses.
    1. Developmental Biology
    2. Evolutionary Biology

    Molecular insights into the origin of the Hox-TALE patterning system

    Bruno Hudry, Morgane Thomas-Chollier ... Samir Merabet
    Interactions between Hox and TALE genes, which generate bilaterally symmetrical body plans, originated in early multicellular animals.
    1. Developmental Biology
    2. Evolutionary Biology

    The evolutionary origin of bilaterian smooth and striated myocytes

    Thibaut Brunet, Antje HL Fischer ... Detlev Arendt
    Molecular profiling of annelid myocytes reveals that the last common protostome-deuterostome ancestor already possessed a dual musculature, with visceral smooth muscles ensuring digestion and somatic striated muscles ensuring locomotion.
    1. Evolutionary Biology
    2. Neuroscience

    Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent expansion of bilaterian and cnidarian peptidergic systems

    Daniel Thiel, Luis Alfonso Yañez Guerra ... Gáspár Jékely
    The identification of 31 neuropeptide GPCRs in the sea anemone Nematostella vectensis provides a rich resource to study peptidergic signaling in cnidarians and suggests that cnidarian and bilaterian peptidergic systems diversified independent from each other from a few ancestral systems.
    1. Evolutionary Biology

    Support for a clade of Placozoa and Cnidaria in genes with minimal compositional bias

    Christopher E Laumer, Harald Gruber-Vodicka ... Gonzalo Giribet
    Protein coding genes strongly support a sister group relationship between Placozoa and Cnidaria to the exclusion of Bilateria, contradicting previous phylogenies, which have likely been misled by pervasive compositional heterogeneity.
    1. Developmental Biology
    2. Evolutionary Biology

    Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm

    Miguel Salinas-Saavedra, Amber Q Rock, Mark Q Martindale
    The expression of 'bilaterian-mesodermal’ genes changes the epithelial properties of the endomesoderm during the embryogenesis of the cnidarian Nematostella vectensis.

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